Stromal Cells Promote Matrix Deposition, Remodelling and an Immunosuppressive Tumour Microenvironment in a 3D Model of Colon Cancer

SIMPLE SUMMARY: Colorectal cancer is the third most common type of cancer in the world. Immune cells and normal supporting cells (MSCs) within a tumour affect patient survival and change how well treatments work. This research aimed to develop a more relevant 3D cancer model that combines MSCs and i...

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Autores principales: Leonard, Niamh A., Reidy, Eileen, Thompson, Kerry, McDermott, Emma, Peerani, Eleonora, Tomas Bort, Elena, Balkwill, Frances R., Loessner, Daniela, Ryan, Aideen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656544/
https://www.ncbi.nlm.nih.gov/pubmed/34885111
http://dx.doi.org/10.3390/cancers13235998

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