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Molecular Activation of the Kv11.1 Channel Reprograms EMT in Colon Cancer by Inhibiting TGFβ Signaling via Activation of Calcineurin
SIMPLE SUMMARY: In metastasis, cancer cells migrate away from the tissue where they first were generated and spread in other body compartments. During this process, stationary epithelial cells undergo multiple biochemical changes to become mesenchymal cells that present enhanced migratory abilities....
Autores principales: | Eskandari, Najmeh, Senyuk, Vitalyi, Moore, Jennifer, Kalik, Zane, Luan, Qiyue, Papautsky, Ian, Moshiri, Arfa, Bocchetta, Maurizio, Salami, Seyed Alireza, Oryan, Shahrbanoo, Gentile, Saverio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656647/ https://www.ncbi.nlm.nih.gov/pubmed/34885136 http://dx.doi.org/10.3390/cancers13236025 |
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