Cargando…
Orai3 Regulates Pancreatic Cancer Metastasis by Encoding a Functional Store Operated Calcium Entry Channel
SIMPLE SUMMARY: Pancreatic cancer (PC) is one of the most lethal forms of cancers with 5-year mean survival rate of less than 10%. Most of the PC associated deaths are due to metastasis to secondary sites. Calcium (Ca(2+)) signaling plays a critical role in regulating hallmarks of cancer progression...
Autores principales: | Arora, Samriddhi, Tanwar, Jyoti, Sharma, Nutan, Saurav, Suman, Motiani, Rajender K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656723/ https://www.ncbi.nlm.nih.gov/pubmed/34885048 http://dx.doi.org/10.3390/cancers13235937 |
Ejemplares similares
-
STIM and Orai1 Variants in Store-Operated Calcium Entry
por: Rosado, Juan A., et al.
Publicado: (2016) -
Dysregulation of host cell calcium signaling during viral infections: Emerging paradigm with high clinical relevance
por: Saurav, Suman, et al.
Publicado: (2021) -
Structures reveal opening of the store-operated calcium channel Orai
por: Hou, Xiaowei, et al.
Publicado: (2018) -
ORAI2 modulates store-operated calcium entry and T cell-mediated immunity
por: Vaeth, Martin, et al.
Publicado: (2017) -
Orai1 and Orai3 in Combination with Stim1 Mediate the Majority of Store-operated Calcium Entry in Astrocytes
por: Kwon, Jea, et al.
Publicado: (2017)