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Association of High-Intensity Exercise with Renal Medullary Carcinoma in Individuals with Sickle Cell Trait: Clinical Observations and Experimental Animal Studies

SIMPLE SUMMARY: Renal medullary carcinoma (RMC) is a rare but highly aggressive malignancy that affects individuals of African descent with sickle cell trait (SCT). The driver of RMC pathogenesis is thought to be renal medullary ischemia from red blood cell sickling in the setting of SCT. Currently,...

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Detalles Bibliográficos
Autores principales: Shapiro, Daniel D., Soeung, Melinda, Perelli, Luigi, Dondossola, Eleonora, Surasi, Devaki Shilpa, Tripathi, Durga N., Bertocchio, Jean-Philippe, Carbone, Federica, Starbuck, Michael W., Van Alstine, Michael L., Rao, Priya, Katz, Matthew H. G., Parker, Nathan H., Shah, Amishi Y., Carugo, Alessandro, Heffernan, Timothy P., Schadler, Keri L., Logothetis, Christopher, Walker, Cheryl L., Wood, Christopher G., Karam, Jose A., Draetta, Giulio F., Tannir, Nizar M., Genovese, Giannicola, Msaouel, Pavlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656882/
https://www.ncbi.nlm.nih.gov/pubmed/34885132
http://dx.doi.org/10.3390/cancers13236022