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Early TP53 Alterations Shape Gastric and Esophageal Cancer Development

SIMPLE SUMMARY: Recent evidence establishes that gastric and esophageal (GE) adenocarcinomas are similar cancers at cellular, genomic, and epigenomic levels. Human GE adenocarcinomas develop TP53 mutations at early stages of malignant progression. This contrasts with other gastrointestinal adenocarc...

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Detalles Bibliográficos
Autores principales:	Sahgal, Pranshu, Huffman, Brandon M., Patil, Deepa T., Chatila, Walid K., Yaeger, Rona, Cleary, James M., Sethi, Nilay S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657039/ https://www.ncbi.nlm.nih.gov/pubmed/34885025 http://dx.doi.org/10.3390/cancers13235915

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