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The Up-regulation of TNF-α Maintains Trigeminal Neuralgia by Modulating MAPKs Phosphorylation and BKCa Channels in Trigeminal Nucleus Caudalis

Trigeminal neuralgia (TN) is a severe chronic neuropathic pain. Despite numerous available medical interventions, the therapeutic effects are not ideal. To control the pain attacks, the need for more contemporary drugs continues to be a real challenge. Our previous study reported that Ca(2+)-activat...

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Detalles Bibliográficos
Autores principales: Lu, Zhan-ying, Fan, Juan, Yu, Li-hua, Ma, Bei, Cheng, Li-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657151/
https://www.ncbi.nlm.nih.gov/pubmed/34899191
http://dx.doi.org/10.3389/fncel.2021.764141