Cargando…

CHFR and Paclitaxel Sensitivity of Ovarian Cancer

SIMPLE SUMMARY: Studies in tissue culture cell lines have indicated that silencing of the mitotic regulator CHFR is associated with increased paclitaxel sensitivity. More recently, it has been suggested that a UBC13-DNMT1-CHFR pathway also modulates sensitivity of ovarian cancer to paclitaxel in the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wahner Hendrickson, Andrea E., Visscher, Daniel W., Hou, Xiaonan, Goergen, Krista M., Atkinson, Hunter J., Beito, Thomas G., Negron, Vivian, Lingle, Wilma L., Bruzek, Amy K., Hurley, Rachel M., Wagner, Jill M., Flatten, Karen S., Peterson, Kevin L., Schneider, Paula A., Larson, Melissa C., Maurer, Matthew J., Kalli, Kimberly R., Oberg, Ann L., Weroha, S. John, Kaufmann, Scott H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657201/ https://www.ncbi.nlm.nih.gov/pubmed/34885153 http://dx.doi.org/10.3390/cancers13236043

Ejemplares similares

Statistical analysis of comparative tumor growth repeated measures experiments in the ovarian cancer patient derived xenograft (PDX) setting
por: Oberg, Ann L., et al.
Publicado: (2021)

Assessment of published models and prognostic variables in epithelial ovarian cancer at Mayo Clinic
por: Hendrickson, Andrea Wahner, et al.
Publicado: (2015)

Methylation of CHFR sensitizes esophageal squamous cell cancer to docetaxel and paclitaxel
por: Yun, Tianyang, et al.
Publicado: (2015)

Control of Centrin Stability by Aurora A
por: Lukasiewicz, Kara B., et al.
Publicado: (2011)

Deciphering CHFR Role in Pancreatic Ductal Adenocarcinoma
por: González-Borja, Iranzu, et al.
Publicado: (2021)

Group III phospholipase A2 downregulation attenuated survival and metastasis in ovarian cancer and promotes chemo-sensitization
por: Ray, Upasana, et al.
Publicado: (2021)

The inhibition of UBC13 expression and blockage of the DNMT1-CHFR-Aurora A pathway contribute to paclitaxel resistance in ovarian cancer
por: Zhang, Xu, et al.
Publicado: (2018)

Chfr and RNF8 synergistically regulate ATM activation
por: Wu, Jiaxue, et al.
Publicado: (2011)

TOPK and PTEN participate in CHFR mediated mitotic checkpoint()
por: Shinde, Swapnil R., et al.
Publicado: (2013)

EGFR as a prognostic biomarker and therapeutic target in ovarian cancer: evaluation of patient cohort and literature review
por: Mehner, Christine, et al.
Publicado: (2017)

Immunodetection of human topoisomerase I-DNA covalent complexes
por: Patel, Anand G., et al.
Publicado: (2016)

CHFR is important for the first wave of ubiquitination at DNA damage sites
por: Liu, Chao, et al.
Publicado: (2013)

Silencing of CHFR Sensitizes Gastric Carcinoma to PARP Inhibitor Treatment
por: Li, Yuan, et al.
Publicado: (2019)

The hypermethylation of the CDKN2A and CHFR promoter region is a key regulatory mechanism of CDKN2A and CHFR expression in esophageal squamous cell carcinoma
por: Mei, Xinyu, et al.
Publicado: (2019)

Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia
por: Honda, T, et al.
Publicado: (2004)

CHFR negatively regulates SIRT1 activity upon oxidative stress
por: Kim, Myungjin, et al.
Publicado: (2016)

Upregulation of the checkpoint protein CHFR is associated with tumor suppression in pancreatic cancers
por: Zhang, Di, et al.
Publicado: (2017)

Repurposing Ceritinib Induces DNA Damage and Enhances PARP Inhibitor Responses in High-Grade Serous Ovarian Carcinoma
por: Kanakkanthara, Arun, et al.
Publicado: (2022)

Overcoming platinum resistance in ovarian cancer by targeting pregnancy-associated plasma protein-A
por: Torres, Diogo, et al.
Publicado: (2019)

Emerging evidence for CHFR as a cancer biomarker: from tumor biology to precision medicine
por: Derks, Sarah, et al.
Publicado: (2013)

Clinicopathological significance of CHFR promoter methylation in gastric cancer: a meta-analysis
por: Ding, Yong, et al.
Publicado: (2017)

Diagnostic and prognostic potential of the microbiome in ovarian cancer treatment response
por: Asangba, Abigail E., et al.
Publicado: (2023)

Chfr acts with the p38 stress kinases to block entry to mitosis in mammalian cells
por: Matsusaka, Takahiro, et al.
Publicado: (2004)

Association between CHFR gene hypermethylation and gastric cancer risk: a meta-analysis
por: Shi, Hua, et al.
Publicado: (2016)

CHFR regulates chemoresistance in triple-negative breast cancer through destabilizing ZEB1
por: Luo, Hong, et al.
Publicado: (2021)

Prevention of Human Lymphoproliferative Tumor Formation in Ovarian Cancer Patient-Derived Xenografts()()
por: Butler, Kristina A., et al.
Publicado: (2017)

Constitutive BAK/MCL1 complexes predict paclitaxel and S63845 sensitivity of ovarian cancer
por: Liu, Dongyan, et al.
Publicado: (2021)

ZC3H18 specifically binds and activates the BRCA1 promoter to facilitate homologous recombination in ovarian cancer
por: Kanakkanthara, Arun, et al.
Publicado: (2019)

Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions
por: Tiruppathi, Chinnaswamy, et al.
Publicado: (2023)

Machine-learning aided in situ drug sensitivity screening predicts treatment outcomes in ovarian PDX tumors
por: Cotler, Max J., et al.
Publicado: (2022)

Correction: Constitutive BAK/MCL1 complexes predict paclitaxel and S63845 sensitivity of ovarian cancer
por: Liu, Dongyan, et al.
Publicado: (2021)

The diagnostic and prognostic value of CHFR hypermethylation in colorectal cancer, a meta-analysis and literature review
por: Sun, Zhulei, et al.
Publicado: (2017)

Association of CHFR Promoter Methylation with Treatment Outcomes of Irinotecan-Based Chemotherapy in Metastatic Colorectal Cancer
por: Cha, Yongjun, et al.
Publicado: (2018)

The Ratios of CD8(+) T Cells to CD4(+)CD25(+) FOXP3(+) and FOXP3(-) T Cells Correlate with Poor Clinical Outcome in Human Serous Ovarian Cancer
por: Preston, Claudia C., et al.
Publicado: (2013)

Small molecule inhibition of the CHFR-PARP1 interaction as novel approach to overcome intrinsic taxane resistance in cancer
por: Brodie, Seth A., et al.
Publicado: (2015)

Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers
por: Mehner, Christine, et al.
Publicado: (2015)

CHFR Promoter Hypermethylation Is Associated with Gastric Cancer and Plays a Protective Role in Gastric Cancer Process
por: Dai, Dongjun, et al.
Publicado: (2019)

Sustained expression of miR-26a promotes chromosomal instability and tumorigenesis through regulation of CHFR
por: Castellano, Leandro, et al.
Publicado: (2017)

Characterization of a RAD51C-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance
por: Hurley, Rachel M, et al.
Publicado: (2021)

Current and Future Directions for PARP Inhibition
por: Grudem, Megan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_v0oumef3mcjnbsisiuv8ofm2oa