Cargando…

Efficacy, Outcome, and Safety of Elderly Patients with Glioblastoma in the 5-ALA Era: Single Center Experience of More Than 10 Years

SIMPLE SUMMARY: In the next decades, the incidence of patients with glioblastoma (GBM) will markedly increase due to the growth of the elderly population. Despite the increasing incidence of GBM, elderly patients are frequently excluded from clinical studies and thus, only few data are available spe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kiesel, Barbara, Wadiura, Lisa I., Mischkulnig, Mario, Makolli, Jessica, Sperl, Veronika, Borkovec, Martin, Freund, Julia, Lang, Alexandra, Millesi, Matthias, Berghoff, Anna S., Furtner, Julia, Woehrer, Adelheid, Widhalm, Georg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657316/ https://www.ncbi.nlm.nih.gov/pubmed/34885227 http://dx.doi.org/10.3390/cancers13236119

Ejemplares similares

Prognostic Value of 5-ALA Fluorescence, Tumor Cell Infiltration and Angiogenesis in the Peritumoral Brain Tissue of Brain Metastases
por: Mercea, Petra A., et al.
Publicado: (2021)

5-ALA Fluorescence Is a Powerful Prognostic Marker during Surgery of Low-Grade Gliomas (WHO Grade II)—Experience at Two Specialized Centers
por: Hosmann, Arthur, et al.
Publicado: (2021)

Comparison of minimal detectable protoporphyrin IX concentrations with a loupe device and conventional 5-ALA fluorescence microscopy: an experimental study
por: Mischkulnig, Mario, et al.
Publicado: (2023)

High Diagnostic Accuracy of Visible 5‐ALA Fluorescence in Meningioma Surgery According to Histopathological Analysis of Tumor Bulk and Peritumoral Tissue
por: Wadiura, Lisa I., et al.
Publicado: (2020)

Reply to Stummer, W.; Thomas, C. Comment on “Hosmann et al. 5-ALA Fluorescence Is a Powerful Prognostic Marker during Surgery of Low-Grade Gliomas (WHO Grade II)—Experience at Two Specialized Centers. Cancers 2021, 13, 2540”
por: Hosmann, Arthur, et al.
Publicado: (2021)

5-ALA in Suspected Low-Grade Gliomas: Current Role, Limitations, and New Approaches
por: Kiesel, Barbara, et al.
Publicado: (2021)

Heme Biosynthesis Factors and 5-ALA Induced Fluorescence: Analysis of mRNA and Protein Expression in Fluorescing and Non-fluorescing Gliomas
por: Mischkulnig, Mario, et al.
Publicado: (2022)

SURG-13. EVALUATION OF 5-ALA FLUORESCENCE IN BRAIN METASTASES OF VARIOUS PRIMARY TUMORS: A MULTICENTER STUDY WITH EXPERIENCE IN 157 CASES
por: Mercea, Petra Andreea, et al.
Publicado: (2019)

High Interobserver Agreement in the Subjective Classification of 5‐Aminolevulinic Acid Fluorescence Levels in Newly Diagnosed Glioblastomas
por: Mischkulnig, Mario, et al.
Publicado: (2020)

The impact of heme biosynthesis regulation on glioma aggressiveness: Correlations with diagnostic molecular markers
por: Mischkulnig, Mario, et al.
Publicado: (2022)

TCGA mRNA Expression Analysis of the Heme Biosynthesis Pathway in Diffusely Infiltrating Gliomas: A Comparison of Typically 5-ALA Fluorescent and Non-Fluorescent Gliomas
por: Mischkulnig, Mario, et al.
Publicado: (2020)

Flavin fluorescence lifetime and autofluorescence optical redox ratio for improved visualization and classification of brain tumors
por: Reichert, David, et al.
Publicado: (2023)

Mapping high-grade glioma immune infiltration to 5-ALA fluorescence levels: TCGA data computation, classical histology, and digital image analysis
por: Lang, Alexandra, et al.
Publicado: (2023)

Heme Biosynthesis mRNA Expression Signature: Towards a Novel Prognostic Biomarker in Patients with Diffusely Infiltrating Gliomas
por: Mischkulnig, Mario, et al.
Publicado: (2021)

Treatment of high-grade glioma patients during the COVID-19 pandemic: Impact on overall survival, tumor size and delay of treatment
por: Mischkulnig, Mario, et al.
Publicado: (2023)

Distributed changes of the functional connectome in patients with glioblastoma
por: Nenning, Karl-Heinz, et al.
Publicado: (2020)

Noninvasive Differentiation of Meningiomas and Dural Metastases Using Intratumoral Vascularity Obtained by Arterial Spin Labeling
por: Furtner, Julia, et al.
Publicado: (2019)

Clinical neuropathology practice guide 1-2013: Molecular subtyping of glioblastoma: ready for clinical use?
por: Woehrer, Adelheid, et al.
Publicado: (2013)

PSMA Expression in 122 Treatment Naive Glioma Patients Related to Tumor Metabolism in (11)C-Methionine PET and Survival
por: Traub-Weidinger, Tatjana, et al.
Publicado: (2021)

The Evoked Potential Score for SSEP and BAEP—A Prognostic Marker for the Long-Term Neurological Outcome in Patients after Poor-Grade Subarachnoid Hemorrhage
por: Wadiura, Lisa I., et al.
Publicado: (2021)

Fluorescence Lifetime Imaging and Spectroscopic Co-Validation for Protoporphyrin IX-Guided Tumor Visualization in Neurosurgery
por: Reichert, David, et al.
Publicado: (2021)

Clinical characteristics and prognostic factors of adult patients with pilocytic astrocytoma
por: Mair, Maximilian J., et al.
Publicado: (2020)

High-resolution metabolic imaging of high-grade gliomas using 7T-CRT-FID-MRSI
por: Hangel, Gilbert, et al.
Publicado: (2020)

BIMG-04. MAPPING HETEROGENEITY OF HIGH-GRADE GLIOMA METABOLISM USING HIGH RESOLUTION 7T MRSI
por: Hangel, Gilbert, et al.
Publicado: (2021)

High correlation of temporal muscle thickness with lumbar skeletal muscle cross-sectional area in patients with brain metastases
por: Leitner, Johannes, et al.
Publicado: (2018)

5-Aminolevulinic Acid Induced Fluorescence Is a Powerful Intraoperative Marker for Precise Histopathological Grading of Gliomas with Non-Significant Contrast-Enhancement
por: Widhalm, Georg, et al.
Publicado: (2013)

LAG-3 expression in the inflammatory microenvironment of glioma
por: Mair, Maximilian J., et al.
Publicado: (2021)

Perioperative imaging in patients treated with resection of brain metastases: a survey by the European Association of Neuro-Oncology (EANO) Youngsters committee
por: Kiesel, Barbara, et al.
Publicado: (2020)

Sex-specific radiomic features of L-[S-methyl-(11)C] methionine PET in patients with newly-diagnosed gliomas in relation to IDH1 predictability
por: Papp, Laszlo, et al.
Publicado: (2023)

Evaluation of the Temporal Muscle Thickness as an Independent Prognostic Biomarker in Patients with Primary Central Nervous System Lymphoma
por: Furtner, Julia, et al.
Publicado: (2021)

Multi-Habitat Radiomics Unravels Distinct Phenotypic Subtypes of Glioblastoma with Clinical and Genomic Significance
por: Choi, Seung Won, et al.
Publicado: (2020)

Preoperative Diffusion-Weighted Imaging of Single Brain Metastases Correlates with Patient Survival Times
por: Berghoff, Anna Sophie, et al.
Publicado: (2013)

Clinical Neuropathology Practice Guide 3-2013: levels of evidence and clinical utility of prognostic and predictive candidate brain tumor biomarkers
por: Berghoff, Anna S., et al.
Publicado: (2013)

Local image variance of 7 Tesla SWI is a new technique for preoperative characterization of diffusely infiltrating gliomas: correlation with tumour grade and IDH1 mutational status
por: Grabner, Günther, et al.
Publicado: (2016)

Clinical Neuropathology practice news 1-2014: Pyrosequencing meets clinical and analytical performance criteria for routine testing of MGMT promoter methylation status in glioblastoma
por: Preusser, Matthias, et al.
Publicado: (2014)

Temporal muscle thickness is an independent prognostic marker in melanoma patients with newly diagnosed brain metastases
por: Furtner, Julia, et al.
Publicado: (2018)

Circulating PD-L1 levels change during bevacizumab-based treatment in recurrent glioma
por: Mair, Maximilian J., et al.
Publicado: (2021)

Macroscopic fluorescence-lifetime imaging of NADH and protoporphyrin IX improves the detection and grading of 5-aminolevulinic acid-stained brain tumors
por: Erkkilä, Mikael T., et al.
Publicado: (2020)

Evaluating cellularity and structural connectivity on whole brain slides using a custom-made digital pathology pipeline
por: Roetzer, Thomas, et al.
Publicado: (2019)

Sarcopenia in Neurological Patients: Standard Values for Temporal Muscle Thickness and Muscle Strength Evaluation
por: Steindl, Ariane, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5886ik5qnlekoodck9su6b0c5g