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Investigation of the Antihypertrophic and Antifibrotic Effects of Losartan in a Rat Model of Radiation-Induced Heart Disease

Radiation-induced heart disease (RIHD) is a potential late side-effect of thoracic radiotherapy resulting in left ventricular hypertrophy (LVH) and fibrosis due to a complex pathomechanism leading to heart failure. Angiotensin-II receptor blockers (ARBs), including losartan, are frequently used to c...

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Detalles Bibliográficos
Autores principales: Kovács, Mónika Gabriella, Kovács, Zsuzsanna Z. A., Varga, Zoltán, Szűcs, Gergő, Freiwan, Marah, Farkas, Katalin, Kővári, Bence, Cserni, Gábor, Kriston, András, Kovács, Ferenc, Horváth, Péter, Földesi, Imre, Csont, Tamás, Kahán, Zsuzsanna, Sárközy, Márta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657420/
https://www.ncbi.nlm.nih.gov/pubmed/34884782
http://dx.doi.org/10.3390/ijms222312963