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Emerging View on the Molecular Functions of Sec62 and Sec63 in Protein Translocation
Most secreted and membrane proteins are targeted to and translocated across the endoplasmic reticulum (ER) membrane through the Sec61 protein-conducting channel. Evolutionarily conserved Sec62 and Sec63 associate with the Sec61 channel, forming the Sec complex and mediating translocation of a subset...
Autores principales: | Jung, Sung-jun, Kim, Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657602/ https://www.ncbi.nlm.nih.gov/pubmed/34884562 http://dx.doi.org/10.3390/ijms222312757 |
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