Cargando…

Unraveling the Spatiotemporal Distribution of VPS13A in the Mouse Brain

Loss-of-function mutations in the human vacuolar protein sorting the 13 homolog A (VPS13A) gene cause Chorea-acanthocytosis (ChAc), with selective degeneration of the striatum as the main neuropathologic feature. Very little is known about the VPS13A expression in the brain. The main objective of th...

Descripción completa

Detalles Bibliográficos
Autores principales:	García-García, Esther, Chaparro-Cabanillas, Nerea, Coll-Manzano, Albert, Carreras-Caballé, Maria, Giralt, Albert, Del Toro, Daniel, Alberch, Jordi, Masana, Mercè, Rodríguez, Manuel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657609/ https://www.ncbi.nlm.nih.gov/pubmed/34884823 http://dx.doi.org/10.3390/ijms222313018

Ejemplares similares

Social Memory and Social Patterns Alterations in the Absence of STriatal-Enriched Protein Tyrosine Phosphatase
por: Blázquez, Gloria, et al.
Publicado: (2019)

Regulation of Hippocampal cGMP Levels as a Candidate to Treat Cognitive Deficits in Huntington’s Disease
por: Saavedra, Ana, et al.
Publicado: (2013)

Neuron‐derived extracellular vesicles contain synaptic proteins, promote spine formation, activate TrkB‐mediated signalling and preserve neuronal complexity
por: Solana‐Balaguer, Julia, et al.
Publicado: (2023)

RTP801/REDD1 Is Involved in Neuroinflammation and Modulates Cognitive Dysfunction in Huntington’s Disease
por: Pérez-Sisqués, Leticia, et al.
Publicado: (2021)

Reduced Fractalkine Levels Lead to Striatal Synaptic Plasticity Deficits in Huntington’s Disease
por: Kim, Anya, et al.
Publicado: (2020)

Meridianins Inhibit GSK3β In Vivo and Improve Behavioral Alterations Induced by Chronic Stress
por: Sancho-Balsells, Anna, et al.
Publicado: (2022)

VPS13A and VPS13C Influence Lipid Droplet Abundance
por: Chen, Shuliang, et al.
Publicado: (2022)

Synaptic RTP801 contributes to motor-learning dysfunction in Huntington’s disease
por: Martín-Flores, Núria, et al.
Publicado: (2020)

Proceedings of the Tenth International Meeting on Neuroacanthocytosis Syndromes
por: Masana, Merc, et al.
Publicado: (2021)

Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction
por: Giralt, Albert, et al.
Publicado: (2011)

VPS13 Forum Proceedings: XK, XK-Related and VPS13 Proteins in Membrane Lipid Dynamics
por: Peikert, Kevin, et al.
Publicado: (2023)

Astrocytic BDNF and TrkB regulate severity and neuronal activity in mouse models of temporal lobe epilepsy
por: Fernández-García, Sara, et al.
Publicado: (2020)

M2 Cortex Circuitry and Sensory-Induced Behavioral Alterations in Huntington's Disease: Role of Superior Colliculus
por: Conde-Berriozabal, Sara, et al.
Publicado: (2023)

VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites
por: Kumar, Nikit, et al.
Publicado: (2018)

Unraveling the Spatiotemporal Human Pluripotency in Embryonic Development
por: Ávila-González, Daniela, et al.
Publicado: (2021)

A VPS13D spastic ataxia mutation disrupts the conserved adaptor-binding site in yeast Vps13
por: Dziurdzik, Samantha K, et al.
Publicado: (2020)

Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies
por: Brito, V, et al.
Publicado: (2013)

Cognitive and Emotional Symptoms Induced by Chronic Stress Are Regulated by EGR1 in a Subpopulation of Hippocampal Pyramidal Neurons
por: Sancho-Balsells, Anna, et al.
Publicado: (2023)

VPS13D promotes peroxisome biogenesis
por: Baldwin, Heather A., et al.
Publicado: (2021)

Targeting Copper Homeostasis Improves Functioning of vps13Δ Yeast Mutant Cells, a Model of VPS13-Related Diseases
por: Soczewka, Piotr, et al.
Publicado: (2021)

Drosophila Vps13 Is Required for Protein Homeostasis in the Brain
por: Vonk, Jan J., et al.
Publicado: (2017)

Vps13 is Required for Efficient Autophagy in Saccharomyces cerevisiae
por: Lei, Yuchen, et al.
Publicado: (2022)

M2 cortex-dorsolateral striatum stimulation reverses motor symptoms and synaptic deficits in Huntington’s disease
por: Fernández-García, Sara, et al.
Publicado: (2020)

Meridianins and Lignarenone B as Potential GSK3β Inhibitors and Inductors of Structural Neuronal Plasticity
por: Llorach-Pares, Laura, et al.
Publicado: (2020)

Meridianins Rescue Cognitive Deficits, Spine Density and Neuroinflammation in the 5xFAD Model of Alzheimer’s Disease
por: Rodríguez-Urgellés, Ened, et al.
Publicado: (2022)

Chorein addiction in VPS13A overexpressing rhabdomyosarcoma cells
por: Honisch, Sabina, et al.
Publicado: (2015)

Selection on VPS13A linked to migration in a songbird
por: Toews, David P. L., et al.
Publicado: (2019)

Structural and biochemical insights into lipid transport by VPS13 proteins
por: Adlakha, Jyoti, et al.
Publicado: (2022)

TBC1D1 interacting proteins, VPS13A and VPS13C, regulate GLUT4 homeostasis in C2C12 myotubes
por: Hook, Sharon C., et al.
Publicado: (2020)

Pyk2 Regulates MAMs and Mitochondrial Dynamics in Hippocampal Neurons
por: López-Molina, Laura, et al.
Publicado: (2022)

Vps13 and Cdc31/centrin: Puzzling partners in membrane traffic
por: Myers, Margaret D., et al.
Publicado: (2017)

Vps13F links bacterial recognition and intracellular killing in Dictyostelium
por: Leiba, Jade, et al.
Publicado: (2017)

Flavonoids as Potential Drugs for VPS13-Dependent Rare Neurodegenerative Diseases
por: Soczewka, Piotr, et al.
Publicado: (2020)

VPS13D bridges the ER to mitochondria and peroxisomes via Miro
por: Guillén-Samander, Andrés, et al.
Publicado: (2021)

A Novel Variant in VPS13B Underlying Cohen Syndrome
por: Hussain, Abrar, et al.
Publicado: (2023)

Endosome to Golgi Retrieval of the Vacuolar Protein Sorting Receptor, Vps10p, Requires the Function of the VPS29, VPS30, and VPS35 Gene Products
por: Seaman, Matthew N.J., et al.
Publicado: (1997)

Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related micro-structural changes
por: Montalban, Enrica, et al.
Publicado: (2019)

The association of lipid transfer protein VPS13A with endosomes is mediated by sorting nexin SNX5
por: Tornero-Écija, Alba, et al.
Publicado: (2023)

A Conserved Function in Phosphatidylinositol Metabolism for Mammalian Vps13 Family Proteins
por: Park, Jae-Sook, et al.
Publicado: (2015)

Yeast Vps13 promotes mitochondrial function and is localized at membrane contact sites
por: Park, Jae-Sook, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_akc50f6rv92i3blb6i9aqpmt89