Cargando…
Drug Repurposing in Rare Diseases: An Integrative Study of Drug Screening and Transcriptomic Analysis in Nephropathic Cystinosis
Diagnosis and cure for rare diseases represent a great challenge for the scientific community who often comes up against the complexity and heterogeneity of clinical picture associated to a high cost and time-consuming drug development processes. Here we show a drug repurposing strategy applied to n...
Autores principales: | Bellomo, Francesco, De Leo, Ester, Taranta, Anna, Giaquinto, Laura, Di Giovamberardino, Gianna, Montefusco, Sandro, Rega, Laura Rita, Pastore, Anna, Medina, Diego Luis, Di Bernardo, Diego, De Matteis, Maria Antonietta, Emma, Francesco |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657658/ https://www.ncbi.nlm.nih.gov/pubmed/34884638 http://dx.doi.org/10.3390/ijms222312829 |
Ejemplares similares
-
Benefits and Toxicity of Disulfiram in Preclinical Models of Nephropathic Cystinosis
por: Taranta, Anna, et al.
Publicado: (2021) -
Analysis of CTNS gene transcripts in nephropathic cystinosis
por: Taranta, Anna, et al.
Publicado: (2010) -
Genistein improves renal disease in a mouse model of nephropathic cystinosis: a comparison study with cysteamine
por: De Leo, Ester, et al.
Publicado: (2022) -
Mitochondrial Dynamics of Proximal Tubular Epithelial Cells in Nephropathic Cystinosis
por: De Rasmo, Domenico, et al.
Publicado: (2019) -
Multisystem involvement, defective lysosomes and impaired autophagy in a novel rat model of nephropathic cystinosis
por: Krohn, Patrick, et al.
Publicado: (2022)