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Incidence of Anxiety in Latest Life and Risk Factors. Results of the AgeCoDe/AgeQualiDe Study
Research on anxiety in oldest-old individuals is scarce. Specifically, incidence studies based on large community samples are lacking. The objective of this study is to assess age- and gender-specific incidence rates in a large sample of oldest-old individuals and to identify potential risk factors....
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657712/ https://www.ncbi.nlm.nih.gov/pubmed/34886512 http://dx.doi.org/10.3390/ijerph182312786 |
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author | Welzel, Franziska Dinah Luppa, Melanie Pabst, Alexander Pentzek, Michael Fuchs, Angela Weeg, Dagmar Bickel, Horst Weyerer, Siegfried Werle, Jochen Wiese, Birgitt Oey, Anke Brettschneider, Christian König, Hans-Helmut Heser, Kathrin van den Bussche, Hendrik Eisele, Marion Maier, Wolfgang Scherer, Martin Wagner, Michael Riedel-Heller, Steffi G. |
author_facet | Welzel, Franziska Dinah Luppa, Melanie Pabst, Alexander Pentzek, Michael Fuchs, Angela Weeg, Dagmar Bickel, Horst Weyerer, Siegfried Werle, Jochen Wiese, Birgitt Oey, Anke Brettschneider, Christian König, Hans-Helmut Heser, Kathrin van den Bussche, Hendrik Eisele, Marion Maier, Wolfgang Scherer, Martin Wagner, Michael Riedel-Heller, Steffi G. |
author_sort | Welzel, Franziska Dinah |
collection | PubMed |
description | Research on anxiety in oldest-old individuals is scarce. Specifically, incidence studies based on large community samples are lacking. The objective of this study is to assess age- and gender-specific incidence rates in a large sample of oldest-old individuals and to identify potential risk factors. The study included data from N = 702 adults aged 81 to 97 years. Anxiety symptoms were identified using the short form of the Geriatric Anxiety Inventory (GAI-SF). Associations of potential risk factors with anxiety incidence were analyzed using Cox proportional hazard models. Out of the N = 702 older adults, N = 77 individuals developed anxiety symptoms during the follow-up period. The incidence rate was 51.3 (95% CI: 41.2–64.1) per 1000 person-years in the overall sample, compared to 58.5 (95% CI: 43.2–72.4) in women and 37.3 (95% CI: 23.6–58.3) in men. Multivariable analysis showed an association of subjective memory complaints (HR: 2.03, 95% CI: 1.16–3.57) and depressive symptoms (HR: 3.20, 95% CI: 1.46–7.01) with incident anxiety in the follow-up. Incident anxiety is highly common in late life. Depressive symptoms and subjective memory complaints are major risk factors of new episodes. Incident anxiety appears to be a response to subjective memory complaints independent of depressive symptoms. |
format | Online Article Text |
id | pubmed-8657712 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86577122021-12-10 Incidence of Anxiety in Latest Life and Risk Factors. Results of the AgeCoDe/AgeQualiDe Study Welzel, Franziska Dinah Luppa, Melanie Pabst, Alexander Pentzek, Michael Fuchs, Angela Weeg, Dagmar Bickel, Horst Weyerer, Siegfried Werle, Jochen Wiese, Birgitt Oey, Anke Brettschneider, Christian König, Hans-Helmut Heser, Kathrin van den Bussche, Hendrik Eisele, Marion Maier, Wolfgang Scherer, Martin Wagner, Michael Riedel-Heller, Steffi G. Int J Environ Res Public Health Article Research on anxiety in oldest-old individuals is scarce. Specifically, incidence studies based on large community samples are lacking. The objective of this study is to assess age- and gender-specific incidence rates in a large sample of oldest-old individuals and to identify potential risk factors. The study included data from N = 702 adults aged 81 to 97 years. Anxiety symptoms were identified using the short form of the Geriatric Anxiety Inventory (GAI-SF). Associations of potential risk factors with anxiety incidence were analyzed using Cox proportional hazard models. Out of the N = 702 older adults, N = 77 individuals developed anxiety symptoms during the follow-up period. The incidence rate was 51.3 (95% CI: 41.2–64.1) per 1000 person-years in the overall sample, compared to 58.5 (95% CI: 43.2–72.4) in women and 37.3 (95% CI: 23.6–58.3) in men. Multivariable analysis showed an association of subjective memory complaints (HR: 2.03, 95% CI: 1.16–3.57) and depressive symptoms (HR: 3.20, 95% CI: 1.46–7.01) with incident anxiety in the follow-up. Incident anxiety is highly common in late life. Depressive symptoms and subjective memory complaints are major risk factors of new episodes. Incident anxiety appears to be a response to subjective memory complaints independent of depressive symptoms. MDPI 2021-12-03 /pmc/articles/PMC8657712/ /pubmed/34886512 http://dx.doi.org/10.3390/ijerph182312786 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Welzel, Franziska Dinah Luppa, Melanie Pabst, Alexander Pentzek, Michael Fuchs, Angela Weeg, Dagmar Bickel, Horst Weyerer, Siegfried Werle, Jochen Wiese, Birgitt Oey, Anke Brettschneider, Christian König, Hans-Helmut Heser, Kathrin van den Bussche, Hendrik Eisele, Marion Maier, Wolfgang Scherer, Martin Wagner, Michael Riedel-Heller, Steffi G. Incidence of Anxiety in Latest Life and Risk Factors. Results of the AgeCoDe/AgeQualiDe Study |
title | Incidence of Anxiety in Latest Life and Risk Factors. Results of the AgeCoDe/AgeQualiDe Study |
title_full | Incidence of Anxiety in Latest Life and Risk Factors. Results of the AgeCoDe/AgeQualiDe Study |
title_fullStr | Incidence of Anxiety in Latest Life and Risk Factors. Results of the AgeCoDe/AgeQualiDe Study |
title_full_unstemmed | Incidence of Anxiety in Latest Life and Risk Factors. Results of the AgeCoDe/AgeQualiDe Study |
title_short | Incidence of Anxiety in Latest Life and Risk Factors. Results of the AgeCoDe/AgeQualiDe Study |
title_sort | incidence of anxiety in latest life and risk factors. results of the agecode/agequalide study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657712/ https://www.ncbi.nlm.nih.gov/pubmed/34886512 http://dx.doi.org/10.3390/ijerph182312786 |
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