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The Effect of Organoselenium Compounds on Histone Deacetylase Inhibition and Their Potential for Cancer Therapy

Genetic and epigenetic changes alter gene expression, contributing to cancer. Epigenetic changes in cancer arise from alterations in DNA and histone modifications that lead to tumour suppressor gene silencing and the activation of oncogenes. The acetylation status of histones and non-histone protein...

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Detalles Bibliográficos
Autores principales: Adimulam, Theolan, Arumugam, Thilona, Foolchand, Ashmika, Ghazi, Terisha, Chuturgoon, Anil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657714/
https://www.ncbi.nlm.nih.gov/pubmed/34884764
http://dx.doi.org/10.3390/ijms222312952

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