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Dityrosine Crosslinking of Collagen and Amyloid-β Peptides Is Formed by Vitamin B(12) Deficiency-Generated Oxidative Stress in Caenorhabditis elegans
(1) Background: Vitamin B(12) deficiency in Caenorhabditis elegans results in severe oxidative stress and induces morphological abnormality in mutants due to disordered cuticle collagen biosynthesis. We clarified the underlying mechanism leading to such mutant worms due to vitamin B(12) deficiency....
Autores principales: | Koseki, Kyohei, Yamamoto, Aoi, Tanimoto, Keisuke, Okamoto, Naho, Teng, Fei, Bito, Tomohiro, Yabuta, Yukinori, Kawano, Tsuyoshi, Watanabe, Fumio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657800/ https://www.ncbi.nlm.nih.gov/pubmed/34884761 http://dx.doi.org/10.3390/ijms222312959 |
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