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Structural Insight into the Binding of TGIF1 to SIN3A PAH2 Domain through a C-Terminal Amphipathic Helix

TGIF1 is a transcriptional repressor playing crucial roles in human development and function and is associated with holoprosencephaly and various cancers. TGIF1-directed transcriptional repression of specific genes depends on the recruitment of corepressor SIN3A. However, to date, the exact region o...

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Detalles Bibliográficos
Autores principales:	He, Xiaoling, Nie, Yao, Zhou, Heng, Hu, Rui, Li, Ying, He, Ting, Zhu, Jiang, Yang, Yunhuang, Liu, Maili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657803/ https://www.ncbi.nlm.nih.gov/pubmed/34884456 http://dx.doi.org/10.3390/ijms222312631

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