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The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer
Immunotherapy is a novel anti-cancer method which employs a different mechanism to conventional treatment. It has become a significant strategy because it provides a better or an alternative option for cancer patients. Recently, immunotherapy has been increasingly approved for the treatment of cance...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657810/ https://www.ncbi.nlm.nih.gov/pubmed/34884642 http://dx.doi.org/10.3390/ijms222312836 |
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author | Chen, Shiu-Jau Wang, Shao-Cheng Chen, Yuan-Chuan |
author_facet | Chen, Shiu-Jau Wang, Shao-Cheng Chen, Yuan-Chuan |
author_sort | Chen, Shiu-Jau |
collection | PubMed |
description | Immunotherapy is a novel anti-cancer method which employs a different mechanism to conventional treatment. It has become a significant strategy because it provides a better or an alternative option for cancer patients. Recently, immunotherapy has been increasingly approved for the treatment of cancer; however, it has various limitations; for instance, it is only suitable for specific patients, the response rate is still low in most cases, etc. Colorectal cancer, lung cancer and pancreatic cancer are known as three major death-causing cancers in most countries. In this review, we discuss immunotherapeutic treatment for these three cancers, and consider the option, prospects and limitations of immunotherapy. The development of immunotherapy should focus on the discovery of biomarkers to screen suitable patients, new targets on tumors, neoadjuvant immunotherapy and the combination of immunotherapy with conventional therapeutic methods. We can expect that immunotherapy potentially will develop as one of the best therapies for patients with advanced cancer or poor responses to traditional methods. |
format | Online Article Text |
id | pubmed-8657810 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86578102021-12-10 The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer Chen, Shiu-Jau Wang, Shao-Cheng Chen, Yuan-Chuan Int J Mol Sci Review Immunotherapy is a novel anti-cancer method which employs a different mechanism to conventional treatment. It has become a significant strategy because it provides a better or an alternative option for cancer patients. Recently, immunotherapy has been increasingly approved for the treatment of cancer; however, it has various limitations; for instance, it is only suitable for specific patients, the response rate is still low in most cases, etc. Colorectal cancer, lung cancer and pancreatic cancer are known as three major death-causing cancers in most countries. In this review, we discuss immunotherapeutic treatment for these three cancers, and consider the option, prospects and limitations of immunotherapy. The development of immunotherapy should focus on the discovery of biomarkers to screen suitable patients, new targets on tumors, neoadjuvant immunotherapy and the combination of immunotherapy with conventional therapeutic methods. We can expect that immunotherapy potentially will develop as one of the best therapies for patients with advanced cancer or poor responses to traditional methods. MDPI 2021-11-27 /pmc/articles/PMC8657810/ /pubmed/34884642 http://dx.doi.org/10.3390/ijms222312836 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Chen, Shiu-Jau Wang, Shao-Cheng Chen, Yuan-Chuan The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer |
title | The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer |
title_full | The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer |
title_fullStr | The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer |
title_full_unstemmed | The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer |
title_short | The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer |
title_sort | immunotherapy for colorectal cancer, lung cancer and pancreatic cancer |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657810/ https://www.ncbi.nlm.nih.gov/pubmed/34884642 http://dx.doi.org/10.3390/ijms222312836 |
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