The ESCRT machinery counteracts Nesprin-2G-mediated mechanical forces during nuclear envelope repair

Transient nuclear envelope ruptures during interphase (NERDI) occur due to cytoskeletal compressive forces at sites of weakened lamina, and delayed NERDI repair results in genomic instability. Nuclear envelope (NE) sealing is completed by endosomal sorting complex required for transport (ESCRT) mach...

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Detalles Bibliográficos
Autores principales: Wallis, Samuel S., Ventimiglia, Leandro N., Otigbah, Evita, Infante, Elvira, Cuesta-Geijo, Miguel Angel, Kidiyoor, Gururaj Rao, Carbajal, M. Alejandra, Fleck, Roland A., Foiani, Marco, Garcia-Manyes, Sergi, Martin-Serrano, Juan, Agromayor, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657813/
https://www.ncbi.nlm.nih.gov/pubmed/34818527
http://dx.doi.org/10.1016/j.devcel.2021.10.022

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