Cargando…

Regulation of the Membrane Trafficking of the Mechanosensitive Ion Channels TRPV1 and TRPV4 by Zonular Tension, Osmotic Stress and Activators in the Mouse Lens

Lens water transport generates a hydrostatic pressure gradient that is regulated by a dual-feedback system that utilizes the mechanosensitive transient receptor potential vanilloid (TRPV) channels, TRPV1 and TRPV4, to sense changes in mechanical tension and extracellular osmolarity. Here, we investi...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakazawa, Yosuke, Petrova, Rosica S., Sugiyama, Yuki, Nagai, Noriaki, Tamura, Hiroomi, Donaldson, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657824/
https://www.ncbi.nlm.nih.gov/pubmed/34884463
http://dx.doi.org/10.3390/ijms222312658