Cargando…

Regulation of the Membrane Trafficking of the Mechanosensitive Ion Channels TRPV1 and TRPV4 by Zonular Tension, Osmotic Stress and Activators in the Mouse Lens

Lens water transport generates a hydrostatic pressure gradient that is regulated by a dual-feedback system that utilizes the mechanosensitive transient receptor potential vanilloid (TRPV) channels, TRPV1 and TRPV4, to sense changes in mechanical tension and extracellular osmolarity. Here, we investi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nakazawa, Yosuke, Petrova, Rosica S., Sugiyama, Yuki, Nagai, Noriaki, Tamura, Hiroomi, Donaldson, Paul J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657824/ https://www.ncbi.nlm.nih.gov/pubmed/34884463 http://dx.doi.org/10.3390/ijms222312658

Ejemplares similares

Modulation of Membrane Trafficking of AQP5 in the Lens in Response to Changes in Zonular Tension Is Mediated by the Mechanosensitive Channel TRPV1
por: Petrova, Rosica S., et al.
Publicado: (2023)

Changes to Zonular Tension Alters the Subcellular Distribution of AQP5 in Regions of Influx and Efflux of Water in the Rat Lens
por: Petrova, Rosica S., et al.
Publicado: (2020)

Effect of Alpha-Glucosyl-Hesperidin Consumption on Lens Sclerosis and Presbyopia
por: Nakazawa, Yosuke, et al.
Publicado: (2021)

Trafficking of Stretch-Regulated TRPV2 and TRPV4 Channels Inferred Through Interactomics
por: Doñate-Macián, Pau, et al.
Publicado: (2019)

Ion Transport Regulation by TRPV4 and TRPV1 in Lens and Ciliary Epithelium
por: Delamere, Nicholas A., et al.
Publicado: (2022)

Degradation of connexin 50 protein causes waterclefts in human lens
por: Nakazawa, Yosuke, et al.
Publicado: (2020)

Signaling Between TRPV1/TRPV4 and Intracellular Hydrostatic Pressure in the Mouse Lens
por: Delamere, Nicholas A., et al.
Publicado: (2020)

Abundant expression and functional participation of TRPV1 at Zusanli acupoint (ST36) in mice: mechanosensitive TRPV1 as an “acupuncture-responding channel”
por: Wu, Shu-Yih, et al.
Publicado: (2014)

TRPV Subfamily (TRPV2, TRPV3, TRPV4, TRPV5, and TRPV6) Gene and Protein Expression in Patients with Ulcerative Colitis
por: Toledo Mauriño, Joel J., et al.
Publicado: (2020)

Fluid shear triggers microvilli formation via mechanosensitive activation of TRPV6
por: Miura, Shigenori, et al.
Publicado: (2015)

Effects of capsular tension ring on surgical outcomes of premium intraocular lens in patients with suspected zonular weakness
por: Miyoshi, Teruyuki, et al.
Publicado: (2020)

Phosphoinositide 3-Kinase Binds to TRPV1 and Mediates NGF-stimulated TRPV1 Trafficking to the Plasma Membrane
por: Stein, Alexander T., et al.
Publicado: (2006)

The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential
por: Shoji, Kenji F, et al.
Publicado: (2023)

Physiological and Pathological Role of TRPV1, TRPV2 and TRPV4 Channels in Heart
por: Gorbunov, Alexandr S., et al.
Publicado: (2019)

Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy
por: Adapala, Ravi K., et al.
Publicado: (2015)

Hesperetin treatment attenuates glycation of lens proteins and advanced‑glycation end products generation
por: Doki, Yuri, et al.
Publicado: (2023)

Phacoemulsification And Zonular Weakness: Contribution Of The Capsular Tension Ring With A Thread
por: Oudjani, Nasreddine, et al.
Publicado: (2019)

Oral consumption of α-glucosyl-hesperidin could prevent lens hardening, which causes presbyopia
por: Nakazawa, Yosuke, et al.
Publicado: (2020)

Influence of glycoprotein MUC1 on trafficking of the Ca(2+)-selective ion channels, TRPV5 and TRPV6, and on in vivo calcium homeostasis
por: Al-bataineh, Mohammad M., et al.
Publicado: (2023)

In-the-bag scleral suturing of intraocular lens in eyes with severe zonular dehiscence
por: Hayashi, K, et al.
Publicado: (2012)

Objective classification of zonular weakness based on lens movement at the start of capsulorhexis
por: Yaguchi, Saori, et al.
Publicado: (2017)

Intrascleral Intraocular Lens Fixation Preserving the Lens Capsule in Cases of Cataract with Insufficient Zonular Support
por: Kato, Mutsuko, et al.
Publicado: (2022)

Rhythmic Trafficking of TRPV2 in the Suprachiasmatic Nucleus is Regulated by Prokineticin 2 Signaling
por: Burton, Katherine J., et al.
Publicado: (2015)

TRPV1-Mediated Sensing of Sodium and Osmotic Pressure in POMC Neurons in the Arcuate Nucleus of the Hypothalamus
por: Zhang, Boyang, et al.
Publicado: (2022)

The Role of Aquaporins in Ocular Lens Homeostasis
por: Schey, Kevin L., et al.
Publicado: (2017)

Activation of the mechanosensitive Ca(2+) channel TRPV4 induces endothelial barrier permeability via the disruption of mitochondrial bioenergetics
por: Lu, Qing, et al.
Publicado: (2020)

Mechanosensitive TRPV4 Channel-Induced Extracellular ATP Accumulation at the Acupoint Mediates Acupuncture Analgesia of Ankle Arthritis in Rats
por: Zheng, Yawen, et al.
Publicado: (2021)

Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension
por: Lakk, Monika, et al.
Publicado: (2021)

Patch clamp studies on TRPV4-dependent hemichannel activation in lens epithelium
por: Ek-Vitorin, Jose F., et al.
Publicado: (2023)

Capsazepine antagonizes TRPV1 activation induced by thermal and osmotic stimuli in human odontoblast-like cells
por: Bernal-Cepeda, Lilia Jadith, et al.
Publicado: (2023)

Placement of dual capsular tension rings for the combined management of traumatic cyclodialysis cleft and zonular dialysis
por: Chen, Jiahui, et al.
Publicado: (2020)

Zonular Cataract and Dental Malformations
Publicado: (1886)

Commentary: Optic capture – An intelligent approach toward intraocular lens placement in zonular laxity
por: Tripathi, Amruta S
Publicado: (2022)

TRPV3 and TRPV4 ion channels are not major contributors to mouse heat sensation
por: Huang, Susan M, et al.
Publicado: (2011)

Urothelial TRPV1: TRPV1-Reporter Mice, a Way to Clarify the Debate?
por: Boudes, Mathieu, et al.
Publicado: (2012)

TRPV1 and TRPV4 Play Pivotal Roles in Delayed Onset Muscle Soreness
por: Ota, Hiroki, et al.
Publicado: (2013)

Monoacylglycerols Activate TRPV1 – A Link between Phospholipase C and TRPV1
por: Zygmunt, Peter M., et al.
Publicado: (2013)

Targeting TRPV1 for Body Weight Control using TRPV1(−/−) Mice and Electroacupuncture
por: Choowanthanapakorn, Monchanok, et al.
Publicado: (2015)

Cinnamaldehyde elicits itch behavior via TRPV1 and TRPV4 but not TRPA1
por: Domocos, Dan, et al.
Publicado: (2020)

Increased capsaicin receptor TRPV1 in skin nerve fibres and related vanilloid receptors TRPV3 and TRPV4 in keratinocytes in human breast pain
por: Gopinath, Preethi, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_2dla4dkvnp1a6g7gq7qer7skmq