Fibroblast Activation Protein Targeted Photodynamic Therapy Selectively Kills Activated Skin Fibroblasts from Systemic Sclerosis Patients and Prevents Tissue Contraction

Systemic sclerosis (SSc) is a rare, severe, auto-immune disease characterized by inflammation, vasculopathy and fibrosis. Activated (myo)fibroblasts are crucial drivers of this fibrosis. By exploiting their expression of fibroblast activation protein (FAP) to perform targeted photodynamic therapy (t...

Descripción completa

Detalles Bibliográficos
Autores principales: Dorst, Daphne N., van Caam, Arjan P. M., Vitters, Elly L., Walgreen, Birgitte, Helsen, Monique M. A., Klein, Christian, Gudi, Shreya, Wubs, Tirza, Kumari, Jyoti, Vonk, Madelon C., van der Kraan, Peter M., Koenders, Marije I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657852/
https://www.ncbi.nlm.nih.gov/pubmed/34884484
http://dx.doi.org/10.3390/ijms222312681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657852/
https://www.ncbi.nlm.nih.gov/pubmed/34884484
http://dx.doi.org/10.3390/ijms222312681

Ejemplares similares