Determination of CYP450 Expression Levels in the Human Small Intestine by Mass Spectrometry-Based Targeted Proteomics

The human small intestine can be involved in the first-pass metabolism of drugs. Under this condition, members of the CYP450 superfamily are expected to contribute to drug presystemic biotransformation. The aim of this study was to quantify protein expression levels of 16 major CYP450 isoforms in ti...

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Detalles Bibliográficos
Autores principales: Grangeon, Alexia, Clermont, Valérie, Barama, Azemi, Gaudette, Fleur, Turgeon, Jacques, Michaud, Veronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657875/
https://www.ncbi.nlm.nih.gov/pubmed/34884595
http://dx.doi.org/10.3390/ijms222312791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657875/
https://www.ncbi.nlm.nih.gov/pubmed/34884595
http://dx.doi.org/10.3390/ijms222312791

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