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Determination of CYP450 Expression Levels in the Human Small Intestine by Mass Spectrometry-Based Targeted Proteomics
The human small intestine can be involved in the first-pass metabolism of drugs. Under this condition, members of the CYP450 superfamily are expected to contribute to drug presystemic biotransformation. The aim of this study was to quantify protein expression levels of 16 major CYP450 isoforms in ti...
Autores principales: | Grangeon, Alexia, Clermont, Valérie, Barama, Azemi, Gaudette, Fleur, Turgeon, Jacques, Michaud, Veronique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657875/ https://www.ncbi.nlm.nih.gov/pubmed/34884595 http://dx.doi.org/10.3390/ijms222312791 |
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