Preparative Biocatalytic Synthesis of α-Ketoglutaramate

α-Ketoglutaramate (KGM) is an underexamined metabolite of L-glutamine in the metabolic pathway of glutaminase II of α-ketoglutarate formation. Presumably, KGM may be a biomarker of hepatic encephalopathy and other hyperammonemic diseases. This metabolite is a substrate for the ω-amidase enzyme and i...

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Detalles Bibliográficos
Autores principales: Nikulin, Maksim, Drobot, Viktor, Švedas, Vytas, Krasnikov, Boris F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657959/
https://www.ncbi.nlm.nih.gov/pubmed/34884551
http://dx.doi.org/10.3390/ijms222312748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657959/
https://www.ncbi.nlm.nih.gov/pubmed/34884551
http://dx.doi.org/10.3390/ijms222312748

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