Cargando…
Fresh and Cryopreserved Human Umbilical-Cord-Derived Mesenchymal Stromal Cells Attenuate Injury and Enhance Resolution and Repair following Ventilation-Induced Lung Injury
Background: Ventilator-induced lung injury (VILI) frequently worsens acute respiratory distress syndrome (ARDS) severity. Human mesenchymal stem/stromal cells (MSCs) offer considerable therapeutic promise, but the key impediments of clinical translation stem from limitations due to cell source and a...
Autores principales: | Horie, Shahd, Gonzalez, Hector, Brady, Jack, Devaney, James, Scully, Michael, O’Toole, Daniel, Laffey, John G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657992/ https://www.ncbi.nlm.nih.gov/pubmed/34884645 http://dx.doi.org/10.3390/ijms222312842 |
Ejemplares similares
-
Cytokine pre-activation of cryopreserved xenogeneic-free human mesenchymal stromal cells enhances resolution and repair following ventilator-induced lung injury potentially via a KGF-dependent mechanism
por: Horie, Shahd, et al.
Publicado: (2020) -
Umbilical cord-derived CD362(+) mesenchymal stromal cells for E. coli pneumonia: impact of dose regimen, passage, cryopreservation, and antibiotic therapy
por: Horie, Shahd, et al.
Publicado: (2020) -
Umbilical Cord-Derived CD362(+) Mesenchymal Stromal Cells Attenuate Polymicrobial Sepsis Induced by Caecal Ligation and Puncture
por: Gonzalez, Hector, et al.
Publicado: (2020) -
Hypercapnic acidosis attenuates pulmonary epithelial stretch-induced injury via inhibition of the canonical NF-κB pathway
por: Horie, Shahd, et al.
Publicado: (2016) -
Mesenchymal stromal cells are more effective than the MSC secretome in diminishing injury and enhancing recovery following ventilator-induced lung injury
por: Hayes, Mairead, et al.
Publicado: (2015)