Targeting S100A9 Reduces Neutrophil Recruitment, Inflammation and Lung Damage in Abdominal Sepsis

S100A9, a pro-inflammatory alarmin, is up-regulated in inflamed tissues. However, the role of S100A9 in regulating neutrophil activation, inflammation and lung damage in sepsis is not known. Herein, we hypothesized that blocking S100A9 function may attenuate neutrophil recruitment in septic lung inj...

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Detalles Bibliográficos
Autores principales: Ding, Zhiyi, Du, Feifei, Averitt V, Richard Garland, Jakobsson, Gabriel, Rönnow, Carl-Fredrik, Rahman, Milladur, Schiopu, Alexandru, Thorlacius, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658007/
https://www.ncbi.nlm.nih.gov/pubmed/34884728
http://dx.doi.org/10.3390/ijms222312923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658007/
https://www.ncbi.nlm.nih.gov/pubmed/34884728
http://dx.doi.org/10.3390/ijms222312923

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