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Targeting S100A9 Reduces Neutrophil Recruitment, Inflammation and Lung Damage in Abdominal Sepsis
S100A9, a pro-inflammatory alarmin, is up-regulated in inflamed tissues. However, the role of S100A9 in regulating neutrophil activation, inflammation and lung damage in sepsis is not known. Herein, we hypothesized that blocking S100A9 function may attenuate neutrophil recruitment in septic lung inj...
Autores principales: | Ding, Zhiyi, Du, Feifei, Averitt V, Richard Garland, Jakobsson, Gabriel, Rönnow, Carl-Fredrik, Rahman, Milladur, Schiopu, Alexandru, Thorlacius, Henrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658007/ https://www.ncbi.nlm.nih.gov/pubmed/34884728 http://dx.doi.org/10.3390/ijms222312923 |
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