Identification of New Compounds with Anticonvulsant and Antinociceptive Properties in a Group of 3-substituted (2,5-dioxo-pyrrolidin-1-yl)(phenyl)-Acetamides

We report herein a series of water-soluble analogues of previously described anticonvulsants and their detailed in vivo and in vitro characterization. The majority of these compounds demonstrated broad-spectrum anticonvulsant properties in animal seizure models, including the maximal electroshock (M...

Descripción completa

Detalles Bibliográficos
Autores principales: Abram, Michał, Jakubiec, Marcin, Rapacz, Anna, Mogilski, Szczepan, Latacz, Gniewomir, Szulczyk, Bartłomiej, Szafarz, Małgorzata, Socała, Katarzyna, Nieoczym, Dorota, Wyska, Elżbieta, Wlaź, Piotr, Kamiński, Rafał M., Kamiński, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658016/
https://www.ncbi.nlm.nih.gov/pubmed/34884898
http://dx.doi.org/10.3390/ijms222313092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658016/
https://www.ncbi.nlm.nih.gov/pubmed/34884898
http://dx.doi.org/10.3390/ijms222313092

Ejemplares similares