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Identification of New Compounds with Anticonvulsant and Antinociceptive Properties in a Group of 3-substituted (2,5-dioxo-pyrrolidin-1-yl)(phenyl)-Acetamides

We report herein a series of water-soluble analogues of previously described anticonvulsants and their detailed in vivo and in vitro characterization. The majority of these compounds demonstrated broad-spectrum anticonvulsant properties in animal seizure models, including the maximal electroshock (M...

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Detalles Bibliográficos
Autores principales:	Abram, Michał, Jakubiec, Marcin, Rapacz, Anna, Mogilski, Szczepan, Latacz, Gniewomir, Szulczyk, Bartłomiej, Szafarz, Małgorzata, Socała, Katarzyna, Nieoczym, Dorota, Wyska, Elżbieta, Wlaź, Piotr, Kamiński, Rafał M., Kamiński, Krzysztof
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658016/ https://www.ncbi.nlm.nih.gov/pubmed/34884898 http://dx.doi.org/10.3390/ijms222313092

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