Cargando…

hnRNPA2B1-Mediated Extracellular Vesicles Sorting of miR-122-5p Potentially Promotes Lung Cancer Progression

Extracellular vesicles (EVs) released by tumor cells play important roles on the remodeling of the tumor–stromal environment and on promoting tumor metastasis. Our earlier studies revealed that miR-122-5p, a type of small non-coding RNA, was dysregulated in non-small cell lung cancer (NSCLC) cell-de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Chuang, Qin, Fang, Wang, Wei, Ni, Yifan, Gao, Mingyu, Guo, Mingxiong, Sun, Guihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658035/ https://www.ncbi.nlm.nih.gov/pubmed/34884671 http://dx.doi.org/10.3390/ijms222312866

Ejemplares similares

Multiple Sclerosis-Associated hnRNPA1 Mutations Alter hnRNPA1 Dynamics and Influence Stress Granule Formation
por: Clarke, Joseph-Patrick W. E., et al.
Publicado: (2021)

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs
por: Villarroya-Beltri, Carolina, et al.
Publicado: (2013)

Monoclonal antibody against H1N1 influenza virus hemagglutinin cross reacts with hnRNPA1 and hnRNPA2/B1
por: Guo, Chunyan, et al.
Publicado: (2020)

Disease mutations in the prion-like domains of hnRNPA1 and hnRNPA2/B1 introduce potent steric zippers that drive excess RNP granule assembly
por: Shorter, James, et al.
Publicado: (2013)

A three-state model for the regulation of telomerase by TERRA and hnRNPA1
por: Redon, Sophie, et al.
Publicado: (2013)

miR-128 Restriction of LINE-1 (L1) Retrotransposition Is Dependent on Targeting hnRNPA1 mRNA
por: Fung, Lianna, et al.
Publicado: (2019)

HnRNPA1 Specifically Recognizes the Base of Nucleotide at the Loop of RNA G-Quadruplex
por: Liu, Xiao, et al.
Publicado: (2018)

hnRNPA2 mediated acetylation reduces telomere length in response to mitochondrial dysfunction
por: Guha, Manti, et al.
Publicado: (2018)

Quercetin Enhances the Anti-Tumor Effects of BET Inhibitors by Suppressing hnRNPA1
por: Pham, Thao N.D., et al.
Publicado: (2019)

Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration
por: Ryan, Veronica H, et al.
Publicado: (2020)

ESCO2 promotes lung adenocarcinoma progression by regulating hnRNPA1 acetylation
por: Zhu, Hui-er, et al.
Publicado: (2021)

Neddylation-mediated degradation of hnRNPA2B1 contributes to hypertriglyceridemia pancreatitis
por: Chen, Wei, et al.
Publicado: (2022)

Increase in hnRNPA1 Expression Suffices to Kill Motor Neurons in Transgenic Rats
por: Huang, Bo, et al.
Publicado: (2023)

Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly
por: Gui, Xinrui, et al.
Publicado: (2019)

Exosomal Transfer of miR-185 Is Controlled by hnRNPA2B1 and Impairs Re-endothelialization After Vascular Injury
por: Si, Yi, et al.
Publicado: (2021)

CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid
por: Lu, Jiahui, et al.
Publicado: (2020)

Tethering-induced destabilization and ATP-binding for tandem RRM domains of ALS-causing TDP-43 and hnRNPA1
por: Dang, Mei, et al.
Publicado: (2021)

High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer
por: Chen, Yahua, et al.
Publicado: (2018)

Structure specific recognition of telomeric repeats containing RNA by the RGG-box of hnRNPA1
por: Ghosh, Meenakshi, et al.
Publicado: (2020)

hnRNPA2B1 Promotes Colon Cancer Progression via the MAPK Pathway
por: Tang, Jingzhi, et al.
Publicado: (2021)

HnRNPA2B1 Aggravates Inflammation by Promoting M1 Macrophage Polarization
por: Meng, Meiyao, et al.
Publicado: (2023)

The interface of condensates of the hnRNPA1 low-complexity domain promotes formation of amyloid fibrils
por: Linsenmeier, Miriam, et al.
Publicado: (2023)

Regulation of hnRNPA1 by microRNAs controls the miR-18a–K-RAS axis in chemotherapy-resistant ovarian cancer
por: Rodriguez-Aguayo, Cristian, et al.
Publicado: (2017)

TERRA and hnRNPA1 Orchestrate an RPA-to-POT1 Switch on Telomeric Single-Stranded DNA
por: Flynn, Rachel Litman, et al.
Publicado: (2011)

Isolated inclusion body myopathy caused by a multisystem proteinopathy–linked hnRNPA1 mutation
por: Izumi, Rumiko, et al.
Publicado: (2015)

Amyotrophic Lateral Sclerosis Type 20 - In Silico Analysis and Molecular Dynamics Simulation of hnRNPA1
por: Krebs, Bruna Baumgarten, et al.
Publicado: (2016)

Functional roles of hnRNPA2/B1 regulated by METTL3 in mammalian embryonic development
por: Kwon, Jeongwoo, et al.
Publicado: (2019)

Interplay of folded domains and the disordered low-complexity domain in mediating hnRNPA1 phase separation
por: Martin, Erik W, et al.
Publicado: (2021)

Clinical heterogeneity in a family with flail arm syndrome and review of hnRNPA1‐related spectrum
por: Han, Xiaochen, et al.
Publicado: (2022)

The RNA-binding protein hnRNPA2 regulates β-catenin protein expression and is overexpressed in prostate cancer
por: Stockley, Jacqueline, et al.
Publicado: (2014)

HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression
por: Guha, Manti, et al.
Publicado: (2016)

Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1
por: Yin, Shu-Yi, et al.
Publicado: (2016)

Structural characterization of the D290V mutation site in hnRNPA2 low-complexity–domain polymers
por: Murray, Dylan T., et al.
Publicado: (2018)

Transcriptome profiling reveals the high incidence of hnRNPA1 exon 8 inclusion in chronic myeloid leukemia
por: Li, Shu-Qi, et al.
Publicado: (2020)

The nuclear localization sequence mediates hnRNPA1 amyloid fibril formation revealed by cryoEM structure
por: Sun, Yunpeng, et al.
Publicado: (2020)

Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth
por: Li, Wen-juan, et al.
Publicado: (2021)

The analgesic and antidepressant properties of dihydroartemisinine in the neuropathic pain mice: By the downregulation of HnRNPA1 in the spinal cord and hippocampus
por: Zhu, Chunyan, et al.
Publicado: (2022)

hnRNPA2B1 regulates the alternative splicing of BIRC5 to promote gastric cancer progression
por: Peng, Wei-zhao, et al.
Publicado: (2021)

Celastrol alleviates comorbid obesity and depression by directly binding amygdala HnRNPA1 in a mouse model
por: Zhu, Chunyan, et al.
Publicado: (2021)

Author Correction: Regulation of hnRNPA1 by microRNAs controls the miR-18a-K-RAS axis in chemotherapy-resistant ovarian cancer
por: Rodriguez-Aguayo, Cristian, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_t9skv5tmd2m7qi8c3d05lmtje6