Cargando…

Neochlorogenic Acid Attenuates Hepatic Lipid Accumulation and Inflammation via Regulating miR-34a In Vitro

Neochlorogenic acid (5-Caffeoylquinic acid; 5-CQA), a major phenolic compound isolated from mulberry leaves, possesses anti-oxidative and anti-inflammatory effects. Although it modulates lipid metabolism, the molecular mechanism is unknown. Using an in-vitro model of nonalcoholic fatty liver disease...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Meng-Hsun, Hung, Tung-Wei, Wang, Chi-Chih, Wu, Sheng-Wen, Yang, Tzu-Wei, Yang, Ching-Yu, Tseng, Tsui-Hwa, Wang, Chau-Jong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658127/ https://www.ncbi.nlm.nih.gov/pubmed/34884968 http://dx.doi.org/10.3390/ijms222313163

Ejemplares similares

Mulberry Leaf and Neochlorogenic Acid Alleviates Glucolipotoxicity-Induced Oxidative Stress and Inhibits Proliferation/Migration via Downregulating Ras and FAK Signaling Pathway in Vascular Smooth Muscle Cell
por: Yang, Tsung-Yuan, et al.
Publicado: (2022)

Study of the fluorescence and interaction between cyclodextrins and neochlorogenic acid, in comparison with chlorogenic acid
por: Navarro-Orcajada, Silvia, et al.
Publicado: (2021)

Mulberry Leaf (Morus alba L.) Extracts and Its Chlorogenic Acid Isomer Component Improve Glucolipotoxicity-Induced Hepatic Lipid Accumulation via Downregulating miR-34a and Decreased Inflammation
por: Yang, Tsung-Yuan, et al.
Publicado: (2022)

Inhibitory Effect of Nelumbo nucifera Leaf Extract on 2-Acetylaminofluorene-induced Hepatocarcinogenesis Through Enhancing Antioxidative Potential and Alleviating Inflammation in Rats
por: Yang, Mon-Yuan, et al.
Publicado: (2019)

Neochlorogenic acid: an anti-HIV active compound identified by screening of Cortex Mori [Morus Alba L. (Moraceae)]
por: Li, Jing, et al.
Publicado: (2021)

Antiadhesive and Antibiofilm Effect of Malvidin-3-Glucoside and Malvidin-3-Glucoside/Neochlorogenic Acid Mixtures upon Staphylococcus
por: Silva, Sara, et al.
Publicado: (2022)

Mulberry leaf extract inhibit hepatocellular carcinoma cell proliferation via depressing IL-6 and TNF-α derived from adipocyte
por: Chang, Chun-Hua, et al.
Publicado: (2018)

The Protective Effect of Adenocaulon himalaicum Edgew. and Its Bioactive Compound Neochlorogenic Acid against UVB-Induced Skin Damage in Human Dermal Fibroblasts and Epidermal Keratinocytes
por: Ahn, Hye Shin, et al.
Publicado: (2021)

Sterol O-acyltransferase 2 chaperoned by apolipoprotein J facilitates hepatic lipid accumulation following viral and nutrient stresses
por: Sun, Hung-Yu, et al.
Publicado: (2021)

Nelumbo nucifera leaves extract attenuate the pathological progression of diabetic nephropathy in high-fat diet-fed and streptozotocin-induced diabetic rats
por: Chen, Huan-Wei, et al.
Publicado: (2019)

Icaritin Attenuates Lipid Accumulation by Increasing Energy Expenditure and Autophagy Regulated by Phosphorylating AMPK
por: Wu, Yue, et al.
Publicado: (2021)

Anti-Inflammatory Effects of Neochlorogenic Acid Extract from Mulberry Leaf (Morus alba L.) Against LPS-Stimulated Inflammatory Response through Mediating the AMPK/Nrf2 Signaling Pathway in A549 Cells
por: Gao, Xiao-han, et al.
Publicado: (2020)

Endoplasmic Reticulum Stress-Induced Resistance to Doxorubicin Is Reversed by Mulberry Leaf Polyphenol Extract in Hepatocellular Carcinoma through Inhibition of COX-2
por: Yang, Mon-Yuan, et al.
Publicado: (2019)

5-Lipoxygenase Activating Protein (FLAP) Dependent Leukotriene Biosynthesis Inhibition (MK591) Attenuates Lipid A Endotoxin-Induced Inflammation
por: Fang, Wen-Feng, et al.
Publicado: (2014)

Gallic Acid Improves Diabetic Steatosis by Downregulating MicroRNA-34a-5p through Targeting NFE2L2 Expression in High-Fat Diet-Fed db/db Mice
por: Lee, Ang-Tse, et al.
Publicado: (2021)

miR-21 attenuates lipopolysaccharide-induced lipid accumulation and inflammatory response: potential role in cerebrovascular disease
por: Feng, Jun, et al.
Publicado: (2014)

A20 Attenuates FFAs-induced Lipid Accumulation in Nonalcoholic Steatohepatitis
por: Ai, Luoyan, et al.
Publicado: (2015)

Urine Glucose Excretion Attenuates the Association Between Lipid Accumulation Product and Serum Uric Acid in Subjects with Prediabetes
por: Chen, Juan, et al.
Publicado: (2020)

Acarbose attenuates migration/proliferation via targeting microRNA-143 in vascular smooth muscle cells under diabetic conditions
por: Chuang, Wei-Yuan, et al.
Publicado: (2020)

Hepatic PKA inhibition accelerates the lipid accumulation in liver
por: Yang, Jining, et al.
Publicado: (2019)

Sirt1 AS lncRNA interacts with its mRNA to inhibit muscle formation by attenuating function of miR-34a
por: Wang, Guo-qiang, et al.
Publicado: (2016)

Acarbose Protects Glucolipotoxicity-Induced Diabetic Nephropathy by Inhibiting Ras Expression in High-Fat Diet-Fed db/db Mice
por: Hung, Tung-Wei, et al.
Publicado: (2022)

Jiao Tai Wan Attenuates Hepatic Lipid Accumulation in Type 2 Diabetes Mellitus
por: Huang, Zhaoyi, et al.
Publicado: (2013)

The Clinical Feature and Treatment Outcome of Ocular Melanoma: A 34-Year Experience in a Tertiary Referral Center
por: Huang, Yu-Yun, et al.
Publicado: (2021)

GRIM-19 Restricts HCV Replication by Attenuating Intracellular Lipid Accumulation
por: Kim, Jung-Hee, et al.
Publicado: (2017)

Hibiscus Anthocyanins Extracts Induce Apoptosis by Activating AMP-Activated Protein Kinase in Human Colorectal Cancer Cells
por: Tsai, Ming-Chang, et al.
Publicado: (2023)

Accumulation of Experience and Newly Developed Devices Can Improve the Safety and Voice Outcome of Total Thyroidectomy for Graves’ Disease
por: Chuang, Cheng-Hsun, et al.
Publicado: (2022)

The caffeic acid moiety plays an essential role in attenuating lipid accumulation by chlorogenic acid and its analogues
por: Cao, Xiaoxue, et al.
Publicado: (2019)

Hospital level variations in the trends and outcomes of the nonoperative management of splenic injuries – a nationwide cohort study
por: Liao, Chien-An, et al.
Publicado: (2019)

PACAP attenuates hepatic lipid accumulation through the FAIM/AMPK/IRβ axis during overnutrition
por: Luo, Wei, et al.
Publicado: (2022)

Xyloketal B Attenuates Fatty Acid-Induced Lipid Accumulation via the SREBP-1c Pathway in NAFLD Models
por: Zhang, Youying, et al.
Publicado: (2017)

A Deep Learning Model for Classification of Endoscopic Gastroesophageal Reflux Disease
por: Wang, Chi-Chih, et al.
Publicado: (2021)

miR-196a enhances polymerization of neuronal microfilaments through suppressing IMP3 and upregulating IGF2 in Huntington’s disease
por: Yang, Han-In, et al.
Publicado: (2022)

Palmiwon attenuates hepatic lipid accumulation and hyperlipidemia in a menopausal rat model
por: Go, Hiroe, et al.
Publicado: (2015)

Lipid accumulation product independently correlate with hepatic steatosis quantified by controlled attenuation parameter in women with polycystic ovary syndrome
por: Zheng, Silan, et al.
Publicado: (2020)

Thermally Activated Delayed Fluorescence in Commercially Available Materials for Solution-Process Exciplex OLEDs
por: Tseng, Zong-Liang, et al.
Publicado: (2021)

Mouse SIRT3 Attenuates Hypertrophy-Related Lipid Accumulation in the Heart through the Deacetylation of LCAD
por: Chen, Tongshuai, et al.
Publicado: (2015)

miR-34a Regulates Lipid Droplet Deposition in 3T3-L1 and C2C12 Cells by Targeting LEF1
por: Wang, Lixue, et al.
Publicado: (2022)

Effects of Dietary Fatty Acid Composition on Lipid Metabolism and Body Fat Accumulation in Ovariectomized Rats
por: Yeh, Jhih-Han, et al.
Publicado: (2021)

Antisense knockdown of pyruvate dehydrogenase kinase promotes the neutral lipid accumulation in the diatom Phaeodactylum tricornutum
por: Ma, Yu-Han, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_el7i08ooa7dr0ve9pkc0ubdvhk