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Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique

Introduction. Our study aimed to determine the feasibility of axillary reverse mapping (ARM) technique, the identification rate of ARM nodes and their metastatic involvement, as well as to identify the factors that influence the identification and metastatic involvement. Material and methods. In tot...

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Autores principales: Caziuc, Alexandra, Schlanger, Diana, Amarinei, Giorgiana, Fagarasan, Vlad, Andras, David, Dindelegan, George Calin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658501/
https://www.ncbi.nlm.nih.gov/pubmed/34884409
http://dx.doi.org/10.3390/jcm10235707
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author Caziuc, Alexandra
Schlanger, Diana
Amarinei, Giorgiana
Fagarasan, Vlad
Andras, David
Dindelegan, George Calin
author_facet Caziuc, Alexandra
Schlanger, Diana
Amarinei, Giorgiana
Fagarasan, Vlad
Andras, David
Dindelegan, George Calin
author_sort Caziuc, Alexandra
collection PubMed
description Introduction. Our study aimed to determine the feasibility of axillary reverse mapping (ARM) technique, the identification rate of ARM nodes and their metastatic involvement, as well as to identify the factors that influence the identification and metastatic involvement. Material and methods. In total, 30 breast cancer patients scheduled for axillary lymph node dissection were enrolled in our study. The lymphatic nodes that drain the arm were identified by injecting 1 mL of blue dye in the ipsilateral upper arm; then, the ARM nodes were resected along with the other lymph nodes and sent for histological evaluation. Results. Identification of ARM node was successful in 18 patients (60%) and 22.22% of the identified ARM lymph nodes had metastatic involvement. Patients with identified ARM nodes had a significant lower BMI and a statistically significant relationship between axillary lymph node status and ARM node metastases was proven. Most of ARM lymph nodes (96.3%) were found above the intercostobrachial nerve, under the axillary vein and lateral to the thoracodorsal bundle. Conclusions. The ARM procedure is easy to reproduce but might not be appropriate for patients with a high BMI. The rate of metastatic involvement of ARM nodes is significant and no factor can predict it, showing that the preservation of these nodes cannot be considered.
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spelling pubmed-86585012021-12-10 Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique Caziuc, Alexandra Schlanger, Diana Amarinei, Giorgiana Fagarasan, Vlad Andras, David Dindelegan, George Calin J Clin Med Article Introduction. Our study aimed to determine the feasibility of axillary reverse mapping (ARM) technique, the identification rate of ARM nodes and their metastatic involvement, as well as to identify the factors that influence the identification and metastatic involvement. Material and methods. In total, 30 breast cancer patients scheduled for axillary lymph node dissection were enrolled in our study. The lymphatic nodes that drain the arm were identified by injecting 1 mL of blue dye in the ipsilateral upper arm; then, the ARM nodes were resected along with the other lymph nodes and sent for histological evaluation. Results. Identification of ARM node was successful in 18 patients (60%) and 22.22% of the identified ARM lymph nodes had metastatic involvement. Patients with identified ARM nodes had a significant lower BMI and a statistically significant relationship between axillary lymph node status and ARM node metastases was proven. Most of ARM lymph nodes (96.3%) were found above the intercostobrachial nerve, under the axillary vein and lateral to the thoracodorsal bundle. Conclusions. The ARM procedure is easy to reproduce but might not be appropriate for patients with a high BMI. The rate of metastatic involvement of ARM nodes is significant and no factor can predict it, showing that the preservation of these nodes cannot be considered. MDPI 2021-12-06 /pmc/articles/PMC8658501/ /pubmed/34884409 http://dx.doi.org/10.3390/jcm10235707 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Caziuc, Alexandra
Schlanger, Diana
Amarinei, Giorgiana
Fagarasan, Vlad
Andras, David
Dindelegan, George Calin
Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique
title Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique
title_full Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique
title_fullStr Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique
title_full_unstemmed Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique
title_short Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique
title_sort preventing breast cancer-related lymphedema: feasibility of axillary reverse mapping technique
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658501/
https://www.ncbi.nlm.nih.gov/pubmed/34884409
http://dx.doi.org/10.3390/jcm10235707
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