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Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique
Introduction. Our study aimed to determine the feasibility of axillary reverse mapping (ARM) technique, the identification rate of ARM nodes and their metastatic involvement, as well as to identify the factors that influence the identification and metastatic involvement. Material and methods. In tot...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658501/ https://www.ncbi.nlm.nih.gov/pubmed/34884409 http://dx.doi.org/10.3390/jcm10235707 |
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author | Caziuc, Alexandra Schlanger, Diana Amarinei, Giorgiana Fagarasan, Vlad Andras, David Dindelegan, George Calin |
author_facet | Caziuc, Alexandra Schlanger, Diana Amarinei, Giorgiana Fagarasan, Vlad Andras, David Dindelegan, George Calin |
author_sort | Caziuc, Alexandra |
collection | PubMed |
description | Introduction. Our study aimed to determine the feasibility of axillary reverse mapping (ARM) technique, the identification rate of ARM nodes and their metastatic involvement, as well as to identify the factors that influence the identification and metastatic involvement. Material and methods. In total, 30 breast cancer patients scheduled for axillary lymph node dissection were enrolled in our study. The lymphatic nodes that drain the arm were identified by injecting 1 mL of blue dye in the ipsilateral upper arm; then, the ARM nodes were resected along with the other lymph nodes and sent for histological evaluation. Results. Identification of ARM node was successful in 18 patients (60%) and 22.22% of the identified ARM lymph nodes had metastatic involvement. Patients with identified ARM nodes had a significant lower BMI and a statistically significant relationship between axillary lymph node status and ARM node metastases was proven. Most of ARM lymph nodes (96.3%) were found above the intercostobrachial nerve, under the axillary vein and lateral to the thoracodorsal bundle. Conclusions. The ARM procedure is easy to reproduce but might not be appropriate for patients with a high BMI. The rate of metastatic involvement of ARM nodes is significant and no factor can predict it, showing that the preservation of these nodes cannot be considered. |
format | Online Article Text |
id | pubmed-8658501 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86585012021-12-10 Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique Caziuc, Alexandra Schlanger, Diana Amarinei, Giorgiana Fagarasan, Vlad Andras, David Dindelegan, George Calin J Clin Med Article Introduction. Our study aimed to determine the feasibility of axillary reverse mapping (ARM) technique, the identification rate of ARM nodes and their metastatic involvement, as well as to identify the factors that influence the identification and metastatic involvement. Material and methods. In total, 30 breast cancer patients scheduled for axillary lymph node dissection were enrolled in our study. The lymphatic nodes that drain the arm were identified by injecting 1 mL of blue dye in the ipsilateral upper arm; then, the ARM nodes were resected along with the other lymph nodes and sent for histological evaluation. Results. Identification of ARM node was successful in 18 patients (60%) and 22.22% of the identified ARM lymph nodes had metastatic involvement. Patients with identified ARM nodes had a significant lower BMI and a statistically significant relationship between axillary lymph node status and ARM node metastases was proven. Most of ARM lymph nodes (96.3%) were found above the intercostobrachial nerve, under the axillary vein and lateral to the thoracodorsal bundle. Conclusions. The ARM procedure is easy to reproduce but might not be appropriate for patients with a high BMI. The rate of metastatic involvement of ARM nodes is significant and no factor can predict it, showing that the preservation of these nodes cannot be considered. MDPI 2021-12-06 /pmc/articles/PMC8658501/ /pubmed/34884409 http://dx.doi.org/10.3390/jcm10235707 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Caziuc, Alexandra Schlanger, Diana Amarinei, Giorgiana Fagarasan, Vlad Andras, David Dindelegan, George Calin Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique |
title | Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique |
title_full | Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique |
title_fullStr | Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique |
title_full_unstemmed | Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique |
title_short | Preventing Breast Cancer-Related Lymphedema: Feasibility of Axillary Reverse Mapping Technique |
title_sort | preventing breast cancer-related lymphedema: feasibility of axillary reverse mapping technique |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658501/ https://www.ncbi.nlm.nih.gov/pubmed/34884409 http://dx.doi.org/10.3390/jcm10235707 |
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