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PHDs/CPT1B/VDAC1 axis regulates long-chain fatty acid oxidation in cardiomyocytes

Cardiac metabolism is a high-oxygen-consuming process, showing a preference for long-chain fatty acid (LCFA) as the fuel source under physiological conditions. However, a metabolic switch (favoring glucose instead of LCFA) is commonly reported in ischemic or late-stage failing hearts. The mechanism...

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Detalles Bibliográficos
Autores principales: Angelini, Aude, Saha, Pradip K., Jain, Antrix, Jung, Sung Yun, Mynatt, Randall L., Pi, Xinchun, Xie, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8658754/
https://www.ncbi.nlm.nih.gov/pubmed/34610308
http://dx.doi.org/10.1016/j.celrep.2021.109767

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