Cargando…

A Validated HPLC-PDA-HRMS Method to Investigate the Biological Stability and Metabolism of Antiparasitic Triterpenic Esters

Pentacyclic triterpenes (PTs) are commonly found in medicinal plants with well-known antiparasitic effects. Previous research on C-3 and C-27 triterpenic esters showed effective and selective in vitro antiparasitic activities and in vivo effectiveness by parenteral routes. The aim of this study was...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schioppa, Laura, Fall, Fanta, Ortiz, Sergio, Poupaert, Jacques H., Quetin-Leclercq, Joelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659078/ https://www.ncbi.nlm.nih.gov/pubmed/34885738 http://dx.doi.org/10.3390/molecules26237154

Ejemplares similares

Design, Synthesis and Biological Activity of C3 Hemisynthetic Triterpenic Esters as Novel Antitrypanosomal Hits
por: Schioppa, Laura, et al.
Publicado: (2021)

In vivo anti-malarial activity and toxicity studies of triterpenic esters isolated form Keetia leucantha and crude extracts
por: Beaufay, Claire, et al.
Publicado: (2017)

HPLC-PDA-ESI-HRMS-Based Profiling of Secondary Metabolites of Rindera graeca Anatomical and Hairy Roots Treated with Drought and Cold Stress
por: Naliwajski, Marcin Robert, et al.
Publicado: (2022)

Identification of antiplasmodial triterpenes from Keetia species using NMR-based metabolic profiling
por: Freire, Rafael Teixeira, et al.
Publicado: (2019)

Fingerprinting Chemical Markers in the Mediterranean Orange Blossom Honey: UHPLC-HRMS Metabolomics Study Integrating Melissopalynological Analysis, GC-MS and HPLC-PDA-ESI/MS
por: Kasiotis, Konstantinos M., et al.
Publicado: (2023)

Profiling of Glucosinolates and Flavonoids in Rorippa indica (Linn.) Hiern. (Cruciferae) by UHPLC-PDA-ESI/HRMS(n)
por: Lin, Long-Ze, et al.
Publicado: (2014)

UHPLC-PDA-ESI/HRMS(n) Profiling Method To Identify and Quantify Oligomeric Proanthocyanidins in Plant Products
por: Lin, Long-Ze, et al.
Publicado: (2014)

HPLC-HRMS Quantification of the Ichthyotoxin Karmitoxin from Karlodinium armiger
por: Andersen, Aaron John Christian, et al.
Publicado: (2017)

Investigation of the transformations of a novel anti-cancer agent combining HPLC, HPLC–MS and direct ESI–HRMS analyses
por: Tietze, Lutz F., et al.
Publicado: (2009)

Evaluation of Antioxidative Mechanisms In Vitro and Triterpenes Composition of Extracts from Silver Birch (Betula pendula Roth) and Black Birch (Betula obscura Kotula) Barks by FT-IR and HPLC-PDA
por: Ostapiuk, Aleksandra, et al.
Publicado: (2021)

Investigation of Antiparasitic Activity of 10 European Tree Bark Extracts on Toxoplasma gondii and Bioguided Identification of Triterpenes in Alnus glutinosa Barks
por: Darme, Pierre, et al.
Publicado: (2022)

Quantitative analysis of anti-inflammatory lignan derivatives in Ratanhiae radix and its tincture by HPLC–PDA and HPLC–MS
por: Baumgartner, Lisa, et al.
Publicado: (2011)

Dereplication and Quantification of Major Compounds of Convolvulus arvensis L. Extracts and Assessment of Their Effect on LPS-Activated J774 Macrophages
por: Abdul Khaliq, Hafiz, et al.
Publicado: (2022)

An HPLC and UHPLC-HRMS approach to study PSMA-11 instability in aqueous solution
por: Iudicello, Antonella, et al.
Publicado: (2021)

Triterpene Esters: Natural Products from Dorstenia arifolia (Moraceae)
por: Fingolo, Catharina E., et al.
Publicado: (2013)

Simultaneous Determination and Quantification of Triterpene Saponins from Camellia sinensis Seeds Using UPLC-PDA-QTOF-MS/MS
por: Wu, Xuejin, et al.
Publicado: (2019)

Application of HPLC–PDA–MS metabolite profiling to investigate the effect of growth temperature and day length on blackcurrant fruit
por: Allwood, J. William, et al.
Publicado: (2019)

Effect of a methanolic extract of Salvadora oleoides Decne. on LPS-activated J774 macrophages, its in vitro and in vivo toxicity study and dereplication of its chemical constituents
por: Khaliq, Hafiz Abdul, et al.
Publicado: (2022)

The Analysis of Phenolic Compounds in Walnut Husk and Pellicle by UPLC-Q-Orbitrap HRMS and HPLC
por: Sheng, Fang, et al.
Publicado: (2021)

Three New Triterpene Esters from Pumpkin (Cucurbita maxima) Seeds
por: Kikuchi, Takashi, et al.
Publicado: (2014)

Phytochemical Analysis of Podospermum and Scorzonera n-Hexane Extracts and the HPLC Quantitation of Triterpenes
por: Bahadır-Acıkara, Özlem, et al.
Publicado: (2018)

Green Extraction of Alkaloids and Polyphenols from Peumus boldus Leaves with Natural Deep Eutectic Solvents and Profiling by HPLC-PDA-IT-MS/MS and HPLC-QTOF-MS/MS
por: Torres-Vega, Jeniffer, et al.
Publicado: (2020)

NMR, RP-HPLC-PDA-ESI-MS(n), and RP-HPLC-FD Characterization of Green and Oolong Teas (Camellia sinensis L.)
por: Sobolev, Anatoly P., et al.
Publicado: (2021)

HPLC-PDA-MS/MS as a strategy to characterize and quantify natural pigments from microalgae
por: Fernandes, Andrêssa S., et al.
Publicado: (2020)

Optimization, Validation and Application of HPLC-PDA Methods for Quantification of Triterpenoids in Vaccinium vitis-idaea L.
por: Vilkickyte, Gabriele, et al.
Publicado: (2021)

Phenolic Profile by HPLC-PDA-MS of Greek Chamomile Populations and Commercial Varieties and Their Antioxidant Activity
por: Tsivelika, Nektaria, et al.
Publicado: (2021)

HPLC-PDA-ESI-MS/MS Profiling and Anti-Biofilm Potential of Eucalyptus sideroxylon Flowers
por: Okba, Mona M., et al.
Publicado: (2021)

Improvement of analytical method for three azo dyes in processed milk and cheese using HPLC-PDA
por: Lee, Se-Jeong, et al.
Publicado: (2023)

Development and validation of an effective and sensitive technique for nitrate determination in fruits and vegetables using HPLC/PDA
por: Uddin, Rayhan, et al.
Publicado: (2023)

Composition Analysis by UPLC-PDA-ESI (−)-HRMS and Antioxidant Activity Using Saccharomyces cerevisiae Model of Herbal Teas and Green Teas from Hainan
por: Li, Hua, et al.
Publicado: (2018)

HPLC, quantitative NMR and HRMS spectroscopic data of nusbiarylins as a new class of antimicrobial agents
por: Qiu, Yangyi, et al.
Publicado: (2020)

Characterization of Corn Silk Extract Using HPLC/HRMS/MS Analyses and Bioinformatic Data Processing
por: Fougère, Laëtitia, et al.
Publicado: (2023)

Investigating the Stability of Six Phenolic TMZ Ester Analogues, Incubated in the Presence of Porcine Liver Esterase and Monitored by HPLC
por: Shervington, Leroy A., et al.
Publicado: (2022)

Novel Triterpenic Acid—Benzotriazole Esters Act as Pro-Apoptotic Antimelanoma Agents
por: Mioc, Marius, et al.
Publicado: (2022)

Rapid Characterization of Triterpene Saponins from Zornia brasiliensis by HPLC-ESI-MS/MS
por: Nascimento, Yuri Mangueira, et al.
Publicado: (2019)

Determining the degradation efficiency and mechanisms of ethyl violet using HPLC-PDA-ESI-MS and GC-MS
por: Chung, Wen-Hsin, et al.
Publicado: (2012)

Antioxidant Capacities and Analysis of Phenolic Compounds in Three Endemic Nolana Species by HPLC-PDA-ESI-MS
por: Simirgiotis, Mario J., et al.
Publicado: (2015)

Development and Validation of an HPLC-PDA Method for Biologically Active Quinonemethide Triterpenoids Isolated from Maytenus chiapensis
por: Taddeo, Vito Alessandro, et al.
Publicado: (2019)

Developing and Validating a Method for Separating Flavonoid Isomers in Common Buckwheat Sprouts Using HPLC-PDA
por: Jang, Davin, et al.
Publicado: (2019)

Pharmacognostic Evaluation and HPLC–PDA and HS–SPME/GC–MS Metabolomic Profiling of Eleutherococcus senticosus Fruits
por: Graczyk, Filip, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_b5n8u392n0mrama79slfjlj9d6