Structural Analysis of Saccharomyces cerevisiae Dihydroorotase Reveals Molecular Insights into the Tetramerization Mechanism

Dihydroorotase (DHOase), a dimetalloenzyme containing a carbamylated lysine within the active site, is a member of the cyclic amidohydrolase family, which also includes allantoinase (ALLase), dihydropyrimidinase (DHPase), hydantoinase, and imidase. Unlike most known cyclic amidohydrolases, which are...

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Detalles Bibliográficos
Autores principales: Guan, Hong-Hsiang, Huang, Yen-Hua, Lin, En-Shyh, Chen, Chun-Jung, Huang, Cheng-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659124/
https://www.ncbi.nlm.nih.gov/pubmed/34885830
http://dx.doi.org/10.3390/molecules26237249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659124/
https://www.ncbi.nlm.nih.gov/pubmed/34885830
http://dx.doi.org/10.3390/molecules26237249

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