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Structural Analysis of Saccharomyces cerevisiae Dihydroorotase Reveals Molecular Insights into the Tetramerization Mechanism
Dihydroorotase (DHOase), a dimetalloenzyme containing a carbamylated lysine within the active site, is a member of the cyclic amidohydrolase family, which also includes allantoinase (ALLase), dihydropyrimidinase (DHPase), hydantoinase, and imidase. Unlike most known cyclic amidohydrolases, which are...
Autores principales: | Guan, Hong-Hsiang, Huang, Yen-Hua, Lin, En-Shyh, Chen, Chun-Jung, Huang, Cheng-Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659124/ https://www.ncbi.nlm.nih.gov/pubmed/34885830 http://dx.doi.org/10.3390/molecules26237249 |
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