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Chemical Composition and Preliminary Toxicity Evaluation of the Essential Oil from Peperomia circinnata Link var. circinnata. (Piperaceae) in Artemia salina Leach

Peperomia Ruiz and Pav, the second largest genus of the Piperaceae, has over the years shown potential biological activities. In this sense, the present work aimed to carry out a seasonal and circadian study on the chemical composition of Peperomia circinata essential oils and aromas, as well as to...

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Autores principales: Mesquita, Késsia do Socorro Miranda, Feitosa, Bruna de Souza, Cruz, Jorddy Neves, Ferreira, Oberdan Oliveira, Franco, Celeste de Jesus Pereira, Cascaes, Márcia Moraes, de Oliveira, Mozaniel Santana, Andrade, Eloisa Helena de Aguiar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659193/
https://www.ncbi.nlm.nih.gov/pubmed/34885940
http://dx.doi.org/10.3390/molecules26237359
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author Mesquita, Késsia do Socorro Miranda
Feitosa, Bruna de Souza
Cruz, Jorddy Neves
Ferreira, Oberdan Oliveira
Franco, Celeste de Jesus Pereira
Cascaes, Márcia Moraes
de Oliveira, Mozaniel Santana
Andrade, Eloisa Helena de Aguiar
author_facet Mesquita, Késsia do Socorro Miranda
Feitosa, Bruna de Souza
Cruz, Jorddy Neves
Ferreira, Oberdan Oliveira
Franco, Celeste de Jesus Pereira
Cascaes, Márcia Moraes
de Oliveira, Mozaniel Santana
Andrade, Eloisa Helena de Aguiar
author_sort Mesquita, Késsia do Socorro Miranda
collection PubMed
description Peperomia Ruiz and Pav, the second largest genus of the Piperaceae, has over the years shown potential biological activities. In this sense, the present work aimed to carry out a seasonal and circadian study on the chemical composition of Peperomia circinata essential oils and aromas, as well as to evaluate the preliminary toxicity in Artemia salina Leach and carry out an in silico study on the interaction mechanism. The chemical composition was characterized by gas chromatography (GC/MS and GC-FID). In the seasonal study the essential oil yields had a variation of 1.2–7.9%, and in the circadian study the variation was 1.5–5.6%. The major compounds in the seasonal study were β-phellandrene and elemicin, in the circadian they were β-phellandrene and myrcene, and the aroma was characterized by the presence of β-phellandrene. The multivariate analysis showed that the period and time of collection influenced the essential oil and aroma chemical composition. The highest toxicity value was observed for the essential oil obtained from the dry material, collected in July with a value of 14.45 ± 0.25 μg·mL(−1), the in silico study showed that the major compounds may be related to potential biological activity demonstrated by the present study.
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spelling pubmed-86591932021-12-10 Chemical Composition and Preliminary Toxicity Evaluation of the Essential Oil from Peperomia circinnata Link var. circinnata. (Piperaceae) in Artemia salina Leach Mesquita, Késsia do Socorro Miranda Feitosa, Bruna de Souza Cruz, Jorddy Neves Ferreira, Oberdan Oliveira Franco, Celeste de Jesus Pereira Cascaes, Márcia Moraes de Oliveira, Mozaniel Santana Andrade, Eloisa Helena de Aguiar Molecules Article Peperomia Ruiz and Pav, the second largest genus of the Piperaceae, has over the years shown potential biological activities. In this sense, the present work aimed to carry out a seasonal and circadian study on the chemical composition of Peperomia circinata essential oils and aromas, as well as to evaluate the preliminary toxicity in Artemia salina Leach and carry out an in silico study on the interaction mechanism. The chemical composition was characterized by gas chromatography (GC/MS and GC-FID). In the seasonal study the essential oil yields had a variation of 1.2–7.9%, and in the circadian study the variation was 1.5–5.6%. The major compounds in the seasonal study were β-phellandrene and elemicin, in the circadian they were β-phellandrene and myrcene, and the aroma was characterized by the presence of β-phellandrene. The multivariate analysis showed that the period and time of collection influenced the essential oil and aroma chemical composition. The highest toxicity value was observed for the essential oil obtained from the dry material, collected in July with a value of 14.45 ± 0.25 μg·mL(−1), the in silico study showed that the major compounds may be related to potential biological activity demonstrated by the present study. MDPI 2021-12-03 /pmc/articles/PMC8659193/ /pubmed/34885940 http://dx.doi.org/10.3390/molecules26237359 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mesquita, Késsia do Socorro Miranda
Feitosa, Bruna de Souza
Cruz, Jorddy Neves
Ferreira, Oberdan Oliveira
Franco, Celeste de Jesus Pereira
Cascaes, Márcia Moraes
de Oliveira, Mozaniel Santana
Andrade, Eloisa Helena de Aguiar
Chemical Composition and Preliminary Toxicity Evaluation of the Essential Oil from Peperomia circinnata Link var. circinnata. (Piperaceae) in Artemia salina Leach
title Chemical Composition and Preliminary Toxicity Evaluation of the Essential Oil from Peperomia circinnata Link var. circinnata. (Piperaceae) in Artemia salina Leach
title_full Chemical Composition and Preliminary Toxicity Evaluation of the Essential Oil from Peperomia circinnata Link var. circinnata. (Piperaceae) in Artemia salina Leach
title_fullStr Chemical Composition and Preliminary Toxicity Evaluation of the Essential Oil from Peperomia circinnata Link var. circinnata. (Piperaceae) in Artemia salina Leach
title_full_unstemmed Chemical Composition and Preliminary Toxicity Evaluation of the Essential Oil from Peperomia circinnata Link var. circinnata. (Piperaceae) in Artemia salina Leach
title_short Chemical Composition and Preliminary Toxicity Evaluation of the Essential Oil from Peperomia circinnata Link var. circinnata. (Piperaceae) in Artemia salina Leach
title_sort chemical composition and preliminary toxicity evaluation of the essential oil from peperomia circinnata link var. circinnata. (piperaceae) in artemia salina leach
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659193/
https://www.ncbi.nlm.nih.gov/pubmed/34885940
http://dx.doi.org/10.3390/molecules26237359
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