A New Kid on the Block: Sacituzumab Govitecan for the Treatment of Breast Cancer and Other Solid Tumors

Human trophoblast cell-surface antigen-2 (Trop-2) is a membrane glycoprotein involved in cell proliferation and motility, frequently overexpressed in epithelial tumors. Thus, it represents an attractive target for anticancer therapies. Sacituzumab govitecan (SG) is a third-generation antibody-drug c...

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Detalles Bibliográficos
Autores principales: Pavone, Giuliana, Motta, Lucia, Martorana, Federica, Motta, Gianmarco, Vigneri, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659286/
https://www.ncbi.nlm.nih.gov/pubmed/34885875
http://dx.doi.org/10.3390/molecules26237294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659286/
https://www.ncbi.nlm.nih.gov/pubmed/34885875
http://dx.doi.org/10.3390/molecules26237294

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