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Optimization of layering technique and secondary structure analysis during the formulation of nanoparticles containing lysozyme by quality by design approach
In our study, core-shell nanoparticles containing lysozyme were formulated with precipitation and layering self-assembly. Factorial design (DoE) was applied by setting the process parameters during the preparation with Quality by Design (QbD) approach. The factors were the concentration of lysozyme...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659335/ https://www.ncbi.nlm.nih.gov/pubmed/34882727 http://dx.doi.org/10.1371/journal.pone.0260603 |