Clinical trials in amyotrophic lateral sclerosis: a systematic review and perspective

Amyotrophic lateral sclerosis is a progressive and devastating neurodegenerative disease. Despite decades of clinical trials, effective disease-modifying drugs remain scarce. To understand the challenges of trial design and delivery, we performed a systematic review of Phase II, Phase II/III and Pha...

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Detalles Bibliográficos
Autores principales: Wong, Charis, Stavrou, Maria, Elliott, Elizabeth, Gregory, Jenna M, Leigh, Nigel, Pinto, Ashwin A, Williams, Timothy L, Chataway, Jeremy, Swingler, Robert, Parmar, Mahesh K B, Stallard, Nigel, Weir, Christopher J, Parker, Richard A, Chaouch, Amina, Hamdalla, Hisham, Ealing, John, Gorrie, George, Morrison, Ian, Duncan, Callum, Connelly, Peter, Carod-Artal, Francisco Javier, Davenport, Richard, Reitboeck, Pablo Garcia, Radunovic, Aleksandar, Srinivasan, Venkataramanan, Preston, Jenny, Mehta, Arpan R, Leighton, Danielle, Glasmacher, Stella, Beswick, Emily, Williamson, Jill, Stenson, Amy, Weaver, Christine, Newton, Judith, Lyle, Dawn, Dakin, Rachel, Macleod, Malcolm, Pal, Suvankar, Chandran, Siddharthan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659356/
https://www.ncbi.nlm.nih.gov/pubmed/34901853
http://dx.doi.org/10.1093/braincomms/fcab242

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