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Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men
As individual sexual behavior is variable over time, the timing of interventions might be vital to reducing HIV transmission. We aimed to investigate transitions between HIV risk levels among men who have sex with men (MSM), and identify determinants associated with behavior change. Participants in...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659368/ https://www.ncbi.nlm.nih.gov/pubmed/34882698 http://dx.doi.org/10.1371/journal.pone.0259913 |
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author | Basten, Maartje G. J. van Wees, Daphne A. Matser, Amy Boyd, Anders Rozhnova, Ganna den Daas, Chantal Kretzschmar, Mirjam E. E. Heijne, Janneke C. M. |
author_facet | Basten, Maartje G. J. van Wees, Daphne A. Matser, Amy Boyd, Anders Rozhnova, Ganna den Daas, Chantal Kretzschmar, Mirjam E. E. Heijne, Janneke C. M. |
author_sort | Basten, Maartje G. J. |
collection | PubMed |
description | As individual sexual behavior is variable over time, the timing of interventions might be vital to reducing HIV transmission. We aimed to investigate transitions between HIV risk levels among men who have sex with men (MSM), and identify determinants associated with behavior change. Participants in a longitudinal cohort study among HIV-negative MSM (Amsterdam Cohort Studies) completed questionnaires about their sexual behavior during biannual visits (2008–2017). Visits were assigned to different HIV risk levels, based on latent classes of behavior. We modelled transitions between risk levels, and identified determinants associated with these transitions at the visit preceding the transition using multi-state Markov models. Based on 7,865 visits of 767 participants, we classified three risk levels: low (73% of visits), medium (22%), and high risk (5%). For MSM at low risk, the six-month probability of increasing risk was 0.11. For MSM at medium risk, the probability of increasing to high risk was 0.08, while the probability of decreasing to low risk was 0.33. For MSM at high risk, the probability of decreasing risk was 0.43. Chemsex, erection stimulants and poppers, high HIV risk perception, and recent STI diagnosis were associated with increased risk at the next visit. High HIV risk perception and young age were associated with decreasing risk. Although the majority of MSM showed no behavior change, a considerable proportion increased HIV risk. Determinants associated with behavior change may help to identify MSM who are likely to increase risk in the near future and target interventions at these individuals, thereby reducing HIV transmission. |
format | Online Article Text |
id | pubmed-8659368 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-86593682021-12-10 Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men Basten, Maartje G. J. van Wees, Daphne A. Matser, Amy Boyd, Anders Rozhnova, Ganna den Daas, Chantal Kretzschmar, Mirjam E. E. Heijne, Janneke C. M. PLoS One Research Article As individual sexual behavior is variable over time, the timing of interventions might be vital to reducing HIV transmission. We aimed to investigate transitions between HIV risk levels among men who have sex with men (MSM), and identify determinants associated with behavior change. Participants in a longitudinal cohort study among HIV-negative MSM (Amsterdam Cohort Studies) completed questionnaires about their sexual behavior during biannual visits (2008–2017). Visits were assigned to different HIV risk levels, based on latent classes of behavior. We modelled transitions between risk levels, and identified determinants associated with these transitions at the visit preceding the transition using multi-state Markov models. Based on 7,865 visits of 767 participants, we classified three risk levels: low (73% of visits), medium (22%), and high risk (5%). For MSM at low risk, the six-month probability of increasing risk was 0.11. For MSM at medium risk, the probability of increasing to high risk was 0.08, while the probability of decreasing to low risk was 0.33. For MSM at high risk, the probability of decreasing risk was 0.43. Chemsex, erection stimulants and poppers, high HIV risk perception, and recent STI diagnosis were associated with increased risk at the next visit. High HIV risk perception and young age were associated with decreasing risk. Although the majority of MSM showed no behavior change, a considerable proportion increased HIV risk. Determinants associated with behavior change may help to identify MSM who are likely to increase risk in the near future and target interventions at these individuals, thereby reducing HIV transmission. Public Library of Science 2021-12-09 /pmc/articles/PMC8659368/ /pubmed/34882698 http://dx.doi.org/10.1371/journal.pone.0259913 Text en © 2021 Basten et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Basten, Maartje G. J. van Wees, Daphne A. Matser, Amy Boyd, Anders Rozhnova, Ganna den Daas, Chantal Kretzschmar, Mirjam E. E. Heijne, Janneke C. M. Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men |
title | Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men |
title_full | Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men |
title_fullStr | Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men |
title_full_unstemmed | Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men |
title_short | Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men |
title_sort | time for change: transitions between hiv risk levels and determinants of behavior change in men who have sex with men |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659368/ https://www.ncbi.nlm.nih.gov/pubmed/34882698 http://dx.doi.org/10.1371/journal.pone.0259913 |
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