Cargando…

Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men

As individual sexual behavior is variable over time, the timing of interventions might be vital to reducing HIV transmission. We aimed to investigate transitions between HIV risk levels among men who have sex with men (MSM), and identify determinants associated with behavior change. Participants in...

Descripción completa

Detalles Bibliográficos
Autores principales: Basten, Maartje G. J., van Wees, Daphne A., Matser, Amy, Boyd, Anders, Rozhnova, Ganna, den Daas, Chantal, Kretzschmar, Mirjam E. E., Heijne, Janneke C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659368/
https://www.ncbi.nlm.nih.gov/pubmed/34882698
http://dx.doi.org/10.1371/journal.pone.0259913
_version_ 1784612947563118592
author Basten, Maartje G. J.
van Wees, Daphne A.
Matser, Amy
Boyd, Anders
Rozhnova, Ganna
den Daas, Chantal
Kretzschmar, Mirjam E. E.
Heijne, Janneke C. M.
author_facet Basten, Maartje G. J.
van Wees, Daphne A.
Matser, Amy
Boyd, Anders
Rozhnova, Ganna
den Daas, Chantal
Kretzschmar, Mirjam E. E.
Heijne, Janneke C. M.
author_sort Basten, Maartje G. J.
collection PubMed
description As individual sexual behavior is variable over time, the timing of interventions might be vital to reducing HIV transmission. We aimed to investigate transitions between HIV risk levels among men who have sex with men (MSM), and identify determinants associated with behavior change. Participants in a longitudinal cohort study among HIV-negative MSM (Amsterdam Cohort Studies) completed questionnaires about their sexual behavior during biannual visits (2008–2017). Visits were assigned to different HIV risk levels, based on latent classes of behavior. We modelled transitions between risk levels, and identified determinants associated with these transitions at the visit preceding the transition using multi-state Markov models. Based on 7,865 visits of 767 participants, we classified three risk levels: low (73% of visits), medium (22%), and high risk (5%). For MSM at low risk, the six-month probability of increasing risk was 0.11. For MSM at medium risk, the probability of increasing to high risk was 0.08, while the probability of decreasing to low risk was 0.33. For MSM at high risk, the probability of decreasing risk was 0.43. Chemsex, erection stimulants and poppers, high HIV risk perception, and recent STI diagnosis were associated with increased risk at the next visit. High HIV risk perception and young age were associated with decreasing risk. Although the majority of MSM showed no behavior change, a considerable proportion increased HIV risk. Determinants associated with behavior change may help to identify MSM who are likely to increase risk in the near future and target interventions at these individuals, thereby reducing HIV transmission.
format Online
Article
Text
id pubmed-8659368
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-86593682021-12-10 Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men Basten, Maartje G. J. van Wees, Daphne A. Matser, Amy Boyd, Anders Rozhnova, Ganna den Daas, Chantal Kretzschmar, Mirjam E. E. Heijne, Janneke C. M. PLoS One Research Article As individual sexual behavior is variable over time, the timing of interventions might be vital to reducing HIV transmission. We aimed to investigate transitions between HIV risk levels among men who have sex with men (MSM), and identify determinants associated with behavior change. Participants in a longitudinal cohort study among HIV-negative MSM (Amsterdam Cohort Studies) completed questionnaires about their sexual behavior during biannual visits (2008–2017). Visits were assigned to different HIV risk levels, based on latent classes of behavior. We modelled transitions between risk levels, and identified determinants associated with these transitions at the visit preceding the transition using multi-state Markov models. Based on 7,865 visits of 767 participants, we classified three risk levels: low (73% of visits), medium (22%), and high risk (5%). For MSM at low risk, the six-month probability of increasing risk was 0.11. For MSM at medium risk, the probability of increasing to high risk was 0.08, while the probability of decreasing to low risk was 0.33. For MSM at high risk, the probability of decreasing risk was 0.43. Chemsex, erection stimulants and poppers, high HIV risk perception, and recent STI diagnosis were associated with increased risk at the next visit. High HIV risk perception and young age were associated with decreasing risk. Although the majority of MSM showed no behavior change, a considerable proportion increased HIV risk. Determinants associated with behavior change may help to identify MSM who are likely to increase risk in the near future and target interventions at these individuals, thereby reducing HIV transmission. Public Library of Science 2021-12-09 /pmc/articles/PMC8659368/ /pubmed/34882698 http://dx.doi.org/10.1371/journal.pone.0259913 Text en © 2021 Basten et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Basten, Maartje G. J.
van Wees, Daphne A.
Matser, Amy
Boyd, Anders
Rozhnova, Ganna
den Daas, Chantal
Kretzschmar, Mirjam E. E.
Heijne, Janneke C. M.
Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men
title Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men
title_full Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men
title_fullStr Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men
title_full_unstemmed Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men
title_short Time for change: Transitions between HIV risk levels and determinants of behavior change in men who have sex with men
title_sort time for change: transitions between hiv risk levels and determinants of behavior change in men who have sex with men
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659368/
https://www.ncbi.nlm.nih.gov/pubmed/34882698
http://dx.doi.org/10.1371/journal.pone.0259913
work_keys_str_mv AT bastenmaartjegj timeforchangetransitionsbetweenhivrisklevelsanddeterminantsofbehaviorchangeinmenwhohavesexwithmen
AT vanweesdaphnea timeforchangetransitionsbetweenhivrisklevelsanddeterminantsofbehaviorchangeinmenwhohavesexwithmen
AT matseramy timeforchangetransitionsbetweenhivrisklevelsanddeterminantsofbehaviorchangeinmenwhohavesexwithmen
AT boydanders timeforchangetransitionsbetweenhivrisklevelsanddeterminantsofbehaviorchangeinmenwhohavesexwithmen
AT rozhnovaganna timeforchangetransitionsbetweenhivrisklevelsanddeterminantsofbehaviorchangeinmenwhohavesexwithmen
AT dendaaschantal timeforchangetransitionsbetweenhivrisklevelsanddeterminantsofbehaviorchangeinmenwhohavesexwithmen
AT kretzschmarmirjamee timeforchangetransitionsbetweenhivrisklevelsanddeterminantsofbehaviorchangeinmenwhohavesexwithmen
AT heijnejannekecm timeforchangetransitionsbetweenhivrisklevelsanddeterminantsofbehaviorchangeinmenwhohavesexwithmen