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Cracking the Skin Barrier: Liquid-Liquid Phase Separation Shines under the Skin
Central to forming and sustaining the skin’s barrier, epidermal keratinocytes (KCs) fluxing to the skin surface undergo a rapid and enigmatic transformation into flat, enucleated squames. At the crux of this transformation are intracellular keratohyalin granules (KGs) that suddenly disappear as term...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659386/ https://www.ncbi.nlm.nih.gov/pubmed/34909733 http://dx.doi.org/10.1016/j.xjidi.2021.100036 |