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Cracking the Skin Barrier: Liquid-Liquid Phase Separation Shines under the Skin

Central to forming and sustaining the skin’s barrier, epidermal keratinocytes (KCs) fluxing to the skin surface undergo a rapid and enigmatic transformation into flat, enucleated squames. At the crux of this transformation are intracellular keratohyalin granules (KGs) that suddenly disappear as term...

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Detalles Bibliográficos
Autores principales: Avecilla, Alexa Regina Chua, Quiroz, Felipe Garcia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659386/
https://www.ncbi.nlm.nih.gov/pubmed/34909733
http://dx.doi.org/10.1016/j.xjidi.2021.100036