A Sensitization-Free Dimethyl Fumarate Prodrug, Isosorbide Di-(Methyl Fumarate), Provides a Topical Treatment Candidate for Psoriasis

Dimethyl fumarate (DMF) is an effective oral treatment for psoriasis administered in Europe for nearly 60 years. However, its potential has been limited by contact dermatitis that prohibits topical application. This paper characterizes a DMF derivative, isosorbide DMF (IDMF), which was designed to h...

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Detalles Bibliográficos
Autores principales: Bojanowski, Krzysztof, Ibeji, Collins U., Singh, Parvesh, Swindell, William R., Chaudhuri, Ratan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659395/
https://www.ncbi.nlm.nih.gov/pubmed/34909741
http://dx.doi.org/10.1016/j.xjidi.2021.100040

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