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In Vitro Cellular Uptake and Transfection of Oligoarginine-Conjugated Glycol Chitosan/siRNA Nanoparticles

Chitosan and its derivatives have been extensively utilized in gene delivery applications because of their low toxicity and positively charged characteristics. However, their low solubility under physiological conditions often limits their application. Glycol chitosan (GC) is a derivative of chitosa...

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Detalles Bibliográficos
Autores principales: Jeong, Eun-Ju, Lee, Jangwook, Kim, Hyun-Seung, Lee, Kuen-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659484/
https://www.ncbi.nlm.nih.gov/pubmed/34883722
http://dx.doi.org/10.3390/polym13234219