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M-Sec induced by HTLV-1 mediates an efficient viral transmission

Human T-cell leukemia virus type 1 (HTLV-1) infects target cells primarily through cell-to-cell routes. Here, we provide evidence that cellular protein M-Sec plays a critical role in this process. When purified and briefly cultured, CD4(+) T cells of HTLV-1 carriers, but not of HTLV-1(-) individuals...

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Detalles Bibliográficos
Autores principales: Hiyoshi, Masateru, Takahashi, Naofumi, Eltalkhawy, Youssef M., Noyori, Osamu, Lotfi, Sameh, Panaampon, Jutatip, Okada, Seiji, Tanaka, Yuetsu, Ueno, Takaharu, Fujisawa, Jun-ichi, Sato, Yuko, Suzuki, Tadaki, Hasegawa, Hideki, Tokunaga, Masahito, Satou, Yorifumi, Yasunaga, Jun-ichirou, Matsuoka, Masao, Utsunomiya, Atae, Suzu, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659635/
https://www.ncbi.nlm.nih.gov/pubmed/34843591
http://dx.doi.org/10.1371/journal.ppat.1010126