Integrating deep learning with microfluidics for biophysical classification of sickle red blood cells adhered to laminin

Sickle cell disease, a genetic disorder affecting a sizeable global demographic, manifests in sickle red blood cells (sRBCs) with altered shape and biomechanics. sRBCs show heightened adhesive interactions with inflamed endothelium, triggering painful vascular occlusion events. Numerous studies empl...

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Detalles Bibliográficos
Autores principales: Praljak, Niksa, Iram, Shamreen, Goreke, Utku, Singh, Gundeep, Hill, Ailis, Gurkan, Umut A., Hinczewski, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659663/
https://www.ncbi.nlm.nih.gov/pubmed/34843453
http://dx.doi.org/10.1371/journal.pcbi.1008946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659663/
https://www.ncbi.nlm.nih.gov/pubmed/34843453
http://dx.doi.org/10.1371/journal.pcbi.1008946

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