Dupilumab Effects on Innate Lymphoid Cell and Helper T Cell Populations in Patients with Atopic Dermatitis

Group 2 innate lymphoid cells (ILCs) are thought to contribute to the pathogenesis of atopic dermatitis (AD). IL-4 stimulates T helper type 2 (Th2) cells and ILC2s to proliferate and produce cytokines. Dupilumab, an antibody against the IL-4 receptor, is used in AD therapy. We speculated that its ef...

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Detalles Bibliográficos
Autores principales: Imai, Yasutomo, Kusakabe, Minori, Nagai, Makoto, Yasuda, Koubun, Yamanishi, Kiyofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659712/
https://www.ncbi.nlm.nih.gov/pubmed/34909707
http://dx.doi.org/10.1016/j.xjidi.2021.100003

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