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Assessing Patient-Specific Microwave Breast Imaging in Clinical Case Studies

Microwave breast imaging has seen increasing use in clinical investigations in the past decade with over eight systems having being trialled with patients. The majority of systems use radar-based algorithms to reconstruct the image shown to the clinician which requires an estimate of the dielectric...

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Autores principales: O’Loughlin, Declan, Elahi, Muhammad Adnan, Lavoie, Benjamin R., Fear, Elise C., O’Halloran, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659731/
https://www.ncbi.nlm.nih.gov/pubmed/34884050
http://dx.doi.org/10.3390/s21238048
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author O’Loughlin, Declan
Elahi, Muhammad Adnan
Lavoie, Benjamin R.
Fear, Elise C.
O’Halloran, Martin
author_facet O’Loughlin, Declan
Elahi, Muhammad Adnan
Lavoie, Benjamin R.
Fear, Elise C.
O’Halloran, Martin
author_sort O’Loughlin, Declan
collection PubMed
description Microwave breast imaging has seen increasing use in clinical investigations in the past decade with over eight systems having being trialled with patients. The majority of systems use radar-based algorithms to reconstruct the image shown to the clinician which requires an estimate of the dielectric properties of the breast to synthetically focus signals to reconstruct the image. Both simulated and experimental studies have shown that, even in simplified scenarios, misestimation of the dielectric properties can impair both the image quality and tumour detection. Many methods have been proposed to address the issue of the estimation of dielectric properties, but few have been tested with patient images. In this work, a leading approach for dielectric properties estimation based on the computation of many candidate images for microwave breast imaging is analysed with patient images for the first time. Using five clinical case studies of both healthy breasts and breasts with abnormalities, the advantages and disadvantages of computational patient-specific microwave breast image reconstruction are highlighted.
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spelling pubmed-86597312021-12-10 Assessing Patient-Specific Microwave Breast Imaging in Clinical Case Studies O’Loughlin, Declan Elahi, Muhammad Adnan Lavoie, Benjamin R. Fear, Elise C. O’Halloran, Martin Sensors (Basel) Article Microwave breast imaging has seen increasing use in clinical investigations in the past decade with over eight systems having being trialled with patients. The majority of systems use radar-based algorithms to reconstruct the image shown to the clinician which requires an estimate of the dielectric properties of the breast to synthetically focus signals to reconstruct the image. Both simulated and experimental studies have shown that, even in simplified scenarios, misestimation of the dielectric properties can impair both the image quality and tumour detection. Many methods have been proposed to address the issue of the estimation of dielectric properties, but few have been tested with patient images. In this work, a leading approach for dielectric properties estimation based on the computation of many candidate images for microwave breast imaging is analysed with patient images for the first time. Using five clinical case studies of both healthy breasts and breasts with abnormalities, the advantages and disadvantages of computational patient-specific microwave breast image reconstruction are highlighted. MDPI 2021-12-01 /pmc/articles/PMC8659731/ /pubmed/34884050 http://dx.doi.org/10.3390/s21238048 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
O’Loughlin, Declan
Elahi, Muhammad Adnan
Lavoie, Benjamin R.
Fear, Elise C.
O’Halloran, Martin
Assessing Patient-Specific Microwave Breast Imaging in Clinical Case Studies
title Assessing Patient-Specific Microwave Breast Imaging in Clinical Case Studies
title_full Assessing Patient-Specific Microwave Breast Imaging in Clinical Case Studies
title_fullStr Assessing Patient-Specific Microwave Breast Imaging in Clinical Case Studies
title_full_unstemmed Assessing Patient-Specific Microwave Breast Imaging in Clinical Case Studies
title_short Assessing Patient-Specific Microwave Breast Imaging in Clinical Case Studies
title_sort assessing patient-specific microwave breast imaging in clinical case studies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659731/
https://www.ncbi.nlm.nih.gov/pubmed/34884050
http://dx.doi.org/10.3390/s21238048
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