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DCNet: Densely Connected Deep Convolutional Encoder–Decoder Network for Nasopharyngeal Carcinoma Segmentation
Nasopharyngeal Carcinoma segmentation in magnetic resonance imagery (MRI) is vital to radiotherapy. Exact dose delivery hinges on an accurate delineation of the gross tumor volume (GTV). However, the large-scale variation in tumor volume is intractable, and the performance of current models is mostl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659888/ https://www.ncbi.nlm.nih.gov/pubmed/34883878 http://dx.doi.org/10.3390/s21237877 |
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author | Li, Yang Han, Guanghui Liu, Xiujian |
author_facet | Li, Yang Han, Guanghui Liu, Xiujian |
author_sort | Li, Yang |
collection | PubMed |
description | Nasopharyngeal Carcinoma segmentation in magnetic resonance imagery (MRI) is vital to radiotherapy. Exact dose delivery hinges on an accurate delineation of the gross tumor volume (GTV). However, the large-scale variation in tumor volume is intractable, and the performance of current models is mostly unsatisfactory with indistinguishable and blurred boundaries of segmentation results of tiny tumor volume. To address the problem, we propose a densely connected deep convolutional network consisting of an encoder network and a corresponding decoder network, which extracts high-level semantic features from different levels and uses low-level spatial features concurrently to obtain fine-grained segmented masks. Skip-connection architecture is involved and modified to propagate spatial information to the decoder network. Preliminary experiments are conducted on 30 patients. Experimental results show our model outperforms all baseline models, with improvements of 4.17%. An ablation study is performed, and the effectiveness of the novel loss function is validated. |
format | Online Article Text |
id | pubmed-8659888 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86598882021-12-10 DCNet: Densely Connected Deep Convolutional Encoder–Decoder Network for Nasopharyngeal Carcinoma Segmentation Li, Yang Han, Guanghui Liu, Xiujian Sensors (Basel) Article Nasopharyngeal Carcinoma segmentation in magnetic resonance imagery (MRI) is vital to radiotherapy. Exact dose delivery hinges on an accurate delineation of the gross tumor volume (GTV). However, the large-scale variation in tumor volume is intractable, and the performance of current models is mostly unsatisfactory with indistinguishable and blurred boundaries of segmentation results of tiny tumor volume. To address the problem, we propose a densely connected deep convolutional network consisting of an encoder network and a corresponding decoder network, which extracts high-level semantic features from different levels and uses low-level spatial features concurrently to obtain fine-grained segmented masks. Skip-connection architecture is involved and modified to propagate spatial information to the decoder network. Preliminary experiments are conducted on 30 patients. Experimental results show our model outperforms all baseline models, with improvements of 4.17%. An ablation study is performed, and the effectiveness of the novel loss function is validated. MDPI 2021-11-26 /pmc/articles/PMC8659888/ /pubmed/34883878 http://dx.doi.org/10.3390/s21237877 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Li, Yang Han, Guanghui Liu, Xiujian DCNet: Densely Connected Deep Convolutional Encoder–Decoder Network for Nasopharyngeal Carcinoma Segmentation |
title | DCNet: Densely Connected Deep Convolutional Encoder–Decoder Network for Nasopharyngeal Carcinoma Segmentation |
title_full | DCNet: Densely Connected Deep Convolutional Encoder–Decoder Network for Nasopharyngeal Carcinoma Segmentation |
title_fullStr | DCNet: Densely Connected Deep Convolutional Encoder–Decoder Network for Nasopharyngeal Carcinoma Segmentation |
title_full_unstemmed | DCNet: Densely Connected Deep Convolutional Encoder–Decoder Network for Nasopharyngeal Carcinoma Segmentation |
title_short | DCNet: Densely Connected Deep Convolutional Encoder–Decoder Network for Nasopharyngeal Carcinoma Segmentation |
title_sort | dcnet: densely connected deep convolutional encoder–decoder network for nasopharyngeal carcinoma segmentation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659888/ https://www.ncbi.nlm.nih.gov/pubmed/34883878 http://dx.doi.org/10.3390/s21237877 |
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