Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling

Hedgehog (HH) morphogen signalling, crucial for cell growth and tissue patterning in animals, is initiated by the binding of dually lipidated HH ligands to cell surface receptors. Hedgehog-Interacting Protein (HHIP), the only reported secreted inhibitor of Sonic Hedgehog (SHH) signalling, binds dire...

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Detalles Bibliográficos
Autores principales: Griffiths, Samuel C., Schwab, Rebekka A., El Omari, Kamel, Bishop, Benjamin, Iverson, Ellen J., Malinauskas, Tomas, Dubey, Ramin, Qian, Mingxing, Covey, Douglas F., Gilbert, Robert J. C., Rohatgi, Rajat, Siebold, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8660895/
https://www.ncbi.nlm.nih.gov/pubmed/34887403
http://dx.doi.org/10.1038/s41467-021-27475-2

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